| 延胡索有效部位提取工艺研究 |
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| 引用本文： | 熊英,杨忠厚,尔凤君.延胡索有效部位提取工艺研究[J].天津药学,2006,18(5):5-7. |
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| 作者姓名： | 熊英 杨忠厚 尔凤君 |
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| 作者单位： | 1. 天津凯阳药业有限公司,天津,300100
2. 天津同仁堂股份有限公司,天津,300132 |
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| 摘 要： | 目的:改进延胡索总生物碱的提取方法,测定延胡索乙素的含量。方法:采用正交法,考察提取方法、提取溶媒、酸碱度等因素,以延胡索乙素为考察指标,用高效液相色谱法测定延胡索乙素含量,寻找延胡索总碱最佳提取工艺。结果:酸碱度对延胡索乙素的得率有极显著的影响。结论:采用碱性乙醇提取最佳。
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| 关 键 词： | 延胡索 延胡索乙素 提取工艺 高效液相色谱法 |
| 文章编号： | 1006-5687（2006）05-0005-03 |
| 收稿时间： | 2005-08-22 |
| 修稿时间： | 2005年8月22日 |
Studies on the extraction technology of corydalis alkaloid from corydalis tuber |
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| Xiong Ying,Yang Zhonghou,Er Fengjun.Studies on the extraction technology of corydalis alkaloid from corydalis tuber[J].Tianjin Pharmacy,2006,18(5):5-7. |
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| Authors: | Xiong Ying Yang Zhonghou Er Fengjun |
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| Affiliation: | 1. Tianjin Kaiyang Pharmaceutial Co Ltd, Tianjin 300100; 2. Tianjin Tongrentang Co Ltd, Tianjin 300132 |
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| Abstract: | Object: To improve the extraction method of corydalis alkaloid,and determine the content of tetrahydropalmatine.Methods: The content of tetrahydropalmatine was determined by HPLC.With the recovery of tetrahydropalmatine as the appraisement standard,the extracting technology including extraction solvents and pH values was optimized by orthogonal design.Results: The extraction recovery was affected remarkably by the value of pH.Conclusion: The best extraction condition was with alcohol(under pH >7) as extraction solvent to extract. |
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| Keywords: | corydalis tuber tetrahydropalmatine extraction technology HPLC content determination |
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