儿童哮喘不同阶段肺炎衣原体感染情况分析 |
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引用本文: | 王健,何莉,李仙梅,刘莲香,邓靖怡.儿童哮喘不同阶段肺炎衣原体感染情况分析[J].医学临床研究,2012,29(8):1509-1510. |
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作者姓名: | 王健 何莉 李仙梅 刘莲香 邓靖怡 |
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作者单位: | 广东省深圳市福田妇幼保健院儿科,广东 深圳,518045 |
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摘 要: | 目的]探讨儿童哮喘各阶段肺炎衣原体(CP)感染状况.方法]对儿童哮喘急性发作期(n=32)、慢性持续期(n=35)和临床缓解期(n=29)及30例健康儿童对照组,用ELISA方法检测肺炎衣原体血清抗体IgA、IgG、IgM.结果]儿童哮喘急性发作期、慢性持续期和临床缓解期,健康儿童CP急性感染率分别为31.3%、25.7%、6.9%和6.6%,慢性感染率分别为18.8%、28.6%、3.5%和0%,儿童哮喘急性发作期与慢性持续期的CP感染率均显著高于临床缓解期及对照组(P<0.05).结论]CP感染是儿童哮喘急性发作期的重要诱因.
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关 键 词: | 哮喘/微生物学 衣原体 肺炎/致病力 衣原体感染/并发症 |
Study on the Relationship Between Chlamydia Pneumoniae Infection and Asthma in Children atDifferent Stages |
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Institution: | WANG Jian, HE Li, LI Xian-mei, et al (Department of Pediatrics, Maternal and Child Health Hospital of Futian District in Shenzhen, Shenzhen 518045, China ) |
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Abstract: | Objective] To explore the relationship between .Chlamydia pneumoniae(CP) infection and asthma in children at different stages. Methods]ELISA was used to detect serum CP antibodies IgA, IgG and IgM in acute attack of asthma children(n= 32), chronic persistence of asthma children(n= 35), clinical remis- sion of asthma children(n--29) and 30 healthy children(control group). Results] Acute infection rates of a- cute attack, chronic persistence and clinical remission of asthma children and healthy children were 31.3~, 25.7%, 6.9% and 6.6~, respectively, and chronic infection rates were 18.8%, 28.6~//oo, 3.5 ~ and 0 ~//0, re- spectively. Statistical analysis showed that the relationship between acute attack of asthma children and CP a- cute infection had statistical significance( P d0.05). The relationship between acute attack of asthma children and CP chronic infection had statistical significant (~(2 ~ 4.27, P d0.05). The relationship between chronic persistence of asthma children and chronic CP infection had statistical significance (X2 = 8. 05, P 〈2 0. 05). Conclusion] CP infection is an important incentive for acute attack of asthma children. |
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Keywords: | Asthma/MI chlamydia pneumoniae/PY chlamdia infections/CO |
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