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CAG治疗急性巨核细胞白血病变为首发的慢性粒细胞白血病(首例报道及文献复习)
引用本文:谢静,何广胜,吴德沛,孙爱宁,金正明,仇惠英,苗瞄,薛胜利,赵晔,王秀丽. CAG治疗急性巨核细胞白血病变为首发的慢性粒细胞白血病(首例报道及文献复习)[J]. 苏州大学学报(自然科学版), 2008, 28(6): 1007-1009
作者姓名:谢静  何广胜  吴德沛  孙爱宁  金正明  仇惠英  苗瞄  薛胜利  赵晔  王秀丽
作者单位:苏州大学附属第一医院,血液科,江苏省血液研究所,卫生部止血与血栓重点实验室,江苏苏州,215006 
基金项目:江苏省青年科技创新人才基金,江苏省135重点学科开放基金,江苏省医学领军人才资助项目,苏州大学附属第一医院优秀青年骨干基金 
摘    要:目的 探讨慢性粒细胞白血病急性巨核细胞白血病变后的表现和治疗方法.方法 报道1例以急性巨核细胞白血病为首发表现的慢性粒细胞白血病(CML),先后予以CAG方案和伊马替尼治疗.结果 该患者获得血液学及分子生物学缓解,且耐受良好.结论 极少数CML患者以急性巨核细胞白血病为首发表现,CAG方案、伊马替尼有较好疗效.

关 键 词:急性巨核细胞白血病变  慢性粒细胞自血病  CAG方案  伊马替尼

CAG Regimen for Chronic Myeloid Leukemia in Megakaryocytic Blast Crisis (the First Case Report and Literature Review)
XIE Jing,HE Guang-sheng,WU De-pei,SUN Ai-ning,JIN Zheng-ming,QIU Hui-ying,MIAO Miao,XUE Sheng-li,ZHAO Ye,WANG Xiu-li. CAG Regimen for Chronic Myeloid Leukemia in Megakaryocytic Blast Crisis (the First Case Report and Literature Review)[J]. Suzhou University Journal of Medical Science, 2008, 28(6): 1007-1009
Authors:XIE Jing  HE Guang-sheng  WU De-pei  SUN Ai-ning  JIN Zheng-ming  QIU Hui-ying  MIAO Miao  XUE Sheng-li  ZHAO Ye  WANG Xiu-li
Affiliation:XIE Jing,HE Guang-sheng,WU De-pei,SUN Ai-ning,JIN Zheng-ming,QIU Hui-ying,MIAO Miao,XUE Sheng-li,ZHAO Ye,WANG Xiu-li(Dept of Hematology,The First Hospital Affiliated to Soochow University,Jiangsu Institute of Hematology,Key Lab of Hemostasis , Thrombosi,Ministry of Health,Jiangsu Suzhou 215006,China)
Abstract:Objective To describe the clinical manifestations of chronic myeloid leukemia in megakaryocytic blast crisis and discuss the therapy for it.Methods One case of megakaryocytic blast crisis was reported as the first presentation of chronic myeloid leukemia and the therapy of CAG and i-matinib.Results The patient achieved the completed hematological and molecular remission.Con-clusion Very rare cases of megakaryocytic crisis have been described as the first presentation of chronic myeloid leukemia,which has a ...
Keywords:megakaryocytic crisis  chronic myeloid leukemia  CAG regimen  imatinib  
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