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益心解毒颗粒对动物心律失常的保护作用
引用本文:高红,杨娟英,卢露,郑伶俐,唐志书.益心解毒颗粒对动物心律失常的保护作用[J].世界中医药,2009,4(4):228-229.
作者姓名:高红  杨娟英  卢露  郑伶俐  唐志书
作者单位:1. 陕西省咸阳市雨茂医院,陕西咸阳中山街135号,712000
2. 咸阳步长制药有限公司
3. 陕西中医学院
摘    要:目的:观察益心解毒颗粒对由CaCl2和乌头碱诱发动物心律失常的保护作用。方法:采用大鼠末次用药60min后,舌下注射CaCl2和乌头碱诱发大鼠心律失常,观察大鼠心电图变化及心律失常情况。结果:益心解毒颗粒3g/kg可明显提高CaCl2心律失常大鼠的存活率 益心解毒颗粒1.5~6.0g/kg可推迟乌头碱致大鼠心律失常的发生时间、缩短心律失常持续时间。结论:益心解毒颗粒对动物心律失常有明显保护作用。

关 键 词:心律失常/中医药疗法  @益心解毒颗粒
收稿时间:2008/4/28 0:00:00

The Protective Effect of Yixin Jiedu Granule on Animals Arrhythmia
Gao Hong,Yang Juanying,Lu Lu.The Protective Effect of Yixin Jiedu Granule on Animals Arrhythmia[J].World Chinese Medicine,2009,4(4):228-229.
Authors:Gao Hong  Yang Juanying  Lu Lu
Institution:Gao Hong Yang Juanying Lu Lu , (Add. : No. 135, Zhongshan Street, Xian'yang, Shaanxi Province, Post code: 712000; 2 Xian' yang Buchang Pharmaceutical Co. , Ltd. 3 Shaanxi College of Chinese Medicine)
Abstract:Objectives:The study is to investigate the effect of Yixin Jiedu Granule on animal arrhythmia induced by CaCl2 and Aconitine.Methods:Sixty minutes later of the last medication, rats were injected sublingually with the CaCl2 or Aconitine, and assessed for any change or arrhythmia on ECG.Results:Yinxin Jiedu Granule at the dosage of 3g/kg significantly raised the survival rate of rats of arrhythmia induced by CaCl2; at the dosage of 1.5-6.0g/kg it postponed the occurrence of arrhythmia induced by Aconitine, and shortened the duration of arrhythmia.Conclusion:Yixin Jiedu Granule has significant protective effect on arrhythmia of lab animals.
Keywords:Arrhythmia  Chinese medical therapy  @Yixin Jiedu Granule
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