Group A streptococcal pyrogenic exotoxin (scarlet fever toxin) type A and blastogen A are the same protein. |
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| Authors: | P. M. Schlievert and E. D. Gray |
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| Affiliation: | Department of Microbiology, University of Minnesota, Minneapolis 55455. |
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| Abstract: | Group A streptococcal pyrogenic exotoxins A, B, and C (also known as scarlet fever toxins and erythrogenic toxins) were evaluated for relatedness to another streptococcus-derived lymphocyte mitogen, blastogen A. Streptococcal pyrogenic exotoxin A and blastogen A were immunologically cross-reactive and shared the same molecular weight, N-terminal amino acid sequence, and capacity to stimulate rabbit splenocyte proliferation nonspecifically. |
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