中国中老年人抑郁症状与其吸烟行为关系的队列研究

目的 探索中老年人抑郁症状与吸烟行为的关联,以及社会人口学特征对这种关联的影响。方法 本研究使用CHARLS2011年与2015年的调查数据,选取基线不吸烟的7 722例中老年人作为研究对象。采用10项流调中心抑郁量表（CES - D10）评估抑郁症状,运用logistic 回归模型分析抑郁症状对吸烟行为的影响。结果 随访4年后,有7.17%（554例）的中老年人出现吸烟行为。logistic回归分析显示,有抑郁症状的中老年人出现吸烟行为的风险是无抑郁症状者的1.35倍（OR = 1.35,95%CI:1.09～1.68）。分层分析发现,与无抑郁症状者相比,有抑郁症状的女性（OR = 1.67,95%CI:1.11～2.52）、45～59岁（OR = 1.52,95%CI:1.11～2.09）、居住地在农村者（OR = 1.55, 95%CI:1.17～2.06）吸烟行为风险更高,差异具有统计学意义 (P＜0.05)。结论 中国中老年人的抑郁症状与吸烟行为显著相关,且在女性、45～59岁和居住在农村的人中更为显著。建议未来的研究进一步探索中老年人临床抑郁与吸烟行为的关系研究。

Cohort study on the association between depressive symptoms and smoking behavior of the middle-aged and elderly in China

To explore the association between depressive symptoms and smoking behavior in middle -aged and elderly people, and interaction effect by sociodemographic characteristics. Methods Using the data of CHARLS in 2011 and 2015, 7722 middle -aged and elderly people who never smoke at baseline were selected as subjects. The depression symptoms were assessed by CES -D10, and the influence of depression symptoms on smoking behavior was analyzed by logistic regression models. Results After 4 years of follow-up, 7.17% (554 cases) of middle-aged and old people had smoking behaviors. Logistic regression analysis showed that the middle -aged and older people with depression were more likely to start smoking than those without depression (OR=1.35, 95% CI:1.09-1.68). Stratified analysis showed that women (OR=1.67,95% CI:1.11-2.52), 45-59 years old (OR=1.52, 95% CI:1.11-2.09), and people living in rural areas (OR=1.55, 95% CI:1.17 -2.06) were more likely to have smoking behaviors than those without depression, respectively. Conclusion The depressive symptoms of middle-aged and elderly people in China are significantly related to smoking behavior, especially in women, people of 45-59 years old and those living in rural areas. It is suggested that future research should further explore the relationship between clinical major depression and smoking behavior in the middle-aged and elderly people.