低分子肝素钠联合气压治疗在预防妇科肿瘤术后下肢深静脉血栓(DVT)的临床效果和应用价值

目的 探讨低分子肝素钠联合气压治疗在预防妇科肿瘤术后下肢深静脉血栓(deep venous thrombosis，DVT)的临床效果和应用价值。方法 选取2016年4月 - 2018年2月收治我院并行肿瘤切除术的恶性肿瘤妇女160例，按照随机数字表法随机分成对照组和观察组，每组80例。对照组患者术后予以低分子肝素钠抗血栓治疗，观察组患者则予以低分子肝素钠抗血栓治疗的基础上联合予以气压治疗。分别对两组患者治疗后的凝血功能、血流速度、下肢周径、DVT发生以及生活质量进行比较。结果 （1）观察组患者的血浆D - 二聚体（D - Dimer,D - D）、纤维蛋白（Fibrin,FIB）以及凝血酶原时间（Prothrombin Time,PT）水平均低于对照组患者，差异有统计学意义（P＜0.05）；（2）观察组患者的下肢血流速度以及下肢周径均优于对照组患者，差异有统计学意义（P＜0.05）；（3）观察组患者的DVT发生率低于对照组患者（P＜0.05）。结论 采用低分子肝素钠联合气压治疗对妇科肿瘤术后患者进行预防血栓治疗，能够有效改善患者血流状态，预防DVT发生，具有重要的临床价值。

Clinical effect and application value of low molecular weight heparin sodium combined with air pressure in the prevention of lower extremity deep vein thrombosis (DVT) after gynecological tumor operation

The aim of this study was to explore the clinical effect and application value of low molecular weight heparin sodium combined with air pressure in the prevention of deep vein thrombosis (DVT) of lower extremity after gynecologic altumor operation. Methods From April 2016 to February 2018, 160 women with malignant tumor who underwent tumor resection in our hospital were randomly divided into control group and observation group, with 80 cases in each group. The patients in the control group were treated with low-molecular-weight heparin sodium for antithrombotic treatment, while the patients in the observation group were treated with low -molecular -weight heparin sodium for antithrombotic treatment combined with air pressure treatment. The coagulation function, blood flow velocity, peripheral diameter of lower extremity, DVT occurrence and quality of life of the two groups were compared. Results 1. The levels of D-dimer, D-D, fibrin and prothromb in time (PT) in the observation group were significantly lower than those in the control group (P<0.05). 2. The blood flow velocity and peripheral track of the lower limbs in the observation group were significantly higher than those in the control group (P<0.05). 3. The incidence of DVT in the observation group was significantly lower than that in the control group (P<0.05). Conclusion Low molecular weight heparin combined with air pressure therapy can effectively improve blood flow and prevent DVT.