特发性右室流出道心律失常患者J波的发生率及其临床特征

目的 调查J波在特发性右室流出道室性心动过速或室性早搏（RVOT-VT/PVCs）病人的发生率及其临床特征。方法 该研究纳入143例特发性 RVOT-VT/PVCs的患者和285例年龄和性别匹配的健康体检者作为对照组。 评估、比较两组间 J-波的发生率。 依据J波的存在与否,将患者分为伴有J波的 RVOT-VT/PVCs组（J-VT/PVCs组）和不伴有J波的 RVOT-VT/PVCs组（non-J-VT/PVCs组）,对两组的临床和电生理数据进行比较。 结果 与对照组比较,J波在特发性 RVOT-VT/PVCs患者中更为常见（39. 9% vs 16. 1% ,P〈0. 01）。 与 non-J-VT/PVCs组比较,J-VT/PVCs组持续性VT、晕厥有较高的发生率,分别为24. 6% vs 4. 7% ;26. 3% vs 2. 3% ,P均〈0.01。 而且VT的周期更短（304±56）ms vs（350±56）ms,P〈0. 01]。 两组中无心室颤动或心脏猝死发生。 结论 特发性RVOT-VT/PVCs患者,有较高的J波发生率;有J波的患者伴随有较严重的心律失常 。

Prevalence and characteristics of idiopathic right ventricular outflow tract arrhythmias associated with J-waves.

Objective To investigate the prevalence and characteristics of idiopathic ventricular tachycardia（VT） or premature ventricular contraction（ PVCs）, originating from right ventricular outflow （RVOT） （RVOT-VT/PVCs） associated with J-waves. Methods The study enrolled 143 consecutive idiopathic RVOT-VT/PVCs patients and 285 age-and gender-matched control subjects. The prevalence of J-waves was assessed in each cohort, and the clinical and electrophysiological data were compared between the RVOT-VT/PVCs patients with J-waves（ J-VT/PVCs group） and those without （non-J- VT/PVCs group）. Results J-waves were more common among patients with idiopathic RVOT-VT/PVCs than among the matched control subjects （39.9% vs 16. 1% ,P〈0.01 ）. The J-VT/PVCs group had a higher incidence of sustained VT （24.6% vs 4.7%, P〈0.01 ）, more episodes of syncope （26.3% vs 2.3%, P〈0.01 ）, and shorter VT cycle length （304±56）ms vs （350±56） ms, P〈0.01 ] than did the non-J-VT/PVCs group. However, no patients demonstrated any ventricular fibrillation （VF） or cardiac sudden death in either group. Conclusions There is a high prevalence of J- waves in the idiopathic RVOT-VT/PVCs patients. Patients with idiopathic RVOT arrhythmias associated with J-waves might have a more enhanced arrhythmogenicity than those without J-waves.