| 胶囊型渗透泵控释制剂的研究进展 |
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| 引用本文： | 周红,胡容峰,桂赟,金栋. 胶囊型渗透泵控释制剂的研究进展[J]. 安徽医药, 2017, 21(6): 983-986. DOI: 10.3969/j.issn.1009-6469.2017.06.003 |
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| 作者姓名： | 周红 胡容峰 桂赟 金栋 |
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| 作者单位： | 安徽中医药大学研究生院,安徽 合肥 230012;省部共建新安医学教育部重点实验室,安徽 合肥 230012;省部共建新安医学教育部重点实验室,安徽 合肥 230012;安徽省"115"新安医药研究与开发创新团队,安徽 合肥 230012;安徽省中药研究与开发重点实验室,安徽 合肥 230012 |
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| 摘 要： | 渗透泵制剂作为目前应用最广和前景较好的缓控释制剂,具有长时间恒速释药、不受胃肠道因素影响、体内外相关性良好等优点,主要包括片剂、胶囊剂等.与渗透泵片剂相比,渗透泵胶囊具有诸多优势,因而受到药物制剂工作者的广泛关注.该文通过查阅近几年国内外相关文献和专利,分类综述了胶囊型渗透泵控释制剂的研究现状.
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| 关 键 词： | 缓控释制剂 恒速释药 渗透泵 胶囊 |
| 收稿时间： | 2016-11-30 |
| 修稿时间： | 2016-12-08 |
Research progress of controlled-release osmotic pump capsules |
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| ZHOU Hong,HU Rongfeng,GUI Yun and JIN Dong. Research progress of controlled-release osmotic pump capsules[J]. Anhui Medical and Pharmaceutical Journal, 2017, 21(6): 983-986. DOI: 10.3969/j.issn.1009-6469.2017.06.003 |
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| Authors: | ZHOU Hong HU Rongfeng GUI Yun JIN Dong |
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| Abstract: | Osmotic pump preparation is the most widely used sustained-controlled release preparation with good future.It could control drug release with constant speed and avoid the influence from the circumstance of gastrointestinal tract.Besides,the release character in vitro of osmotic pump has good correlation with absorption in vivo.Osmotic pump preparation mainly includes tablets,capsules and so on.Compared with the osmotic pump tablets,osmotic pump capsules have many advantages and have received widespread attention.In this article,the research status of controlled-release osmotic pump capsules is reviewed by retrieving the relevant literature and patents in recent years. |
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| Keywords: | Sustained-controlled release preparation Constant drug release Osmotic pump Capsule |
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