益生菌治疗新生儿喂养不耐受疗效分析

目的 研究益生菌治疗新生儿喂养不耐受的临床疗效.方法 选择新生儿喂养不耐受患儿50例,采用随机数字表法分成两组,对照组25例给予治疗原发病,早期微量喂养,必要时静脉营养等;治疗组25例在上述治疗基础上加用益生菌口服,观察两组患儿呕吐停止时间、腹胀消失时间、达全胃肠道喂养时间、住院天数及治疗有效率.结果 治疗组与对照组的呕吐停止时间分别为(2.4±0.1)d与(3.6±0.2)d;腹胀消失时间分别为(2.6±0.1)d与(3.8±0.2)d;达全胃肠道喂养时间分别为(6.7±0.2)d与(8.1±0.1)d;住院天数分别为(7.7±0.1)d与(8.9±0.1)d;治疗有效率分别为96％与68％,两组均差异有统计学意义(P＜0.05).结论 益生菌治疗新生儿喂养不耐受可减轻呕吐、腹胀症状、促进肠内营养的恢复,缩短病程,疗效确切,值得临床推广.

Analysis of the efficacy of probiotics in the treatment of neonatal feeding intolerance

Objective To observe the clinical efficacy of probiotics in treatment of neonatal feeding intolerance.Methods Fifty children with neonatal feeding intolerance were obtained.The participants were randomly divided into two groups,the control group (25 cases) received treatment of primary disease,early micro feeding,parenteral nutrition when necessary etc.and the treatment group (25 cases),receiving oral probiotics,on the basis of the above treatment.Vomiting stop time,abdominal distension disappear time,the gastrointestinal tract feeding time,hospitalization days and treatment efficiency in both groups were observed.Results In the treatment group and control group,the vomiting stop time was (2.4 ± 0.1) d and (3.6 ± 0.2) d separately.Abdominal distension disappear time was (2.6 ± 0.1) d and (3.80 ± 0.2) d,the gastrointestinal tract feeding time was (6.7 ± 0.2) d and (8.1 ± 0.1) d,hospitalization days was (7.7 ± 0.1) d and (8.9 ± 0.1) d,treatment efficiency was 96 ％ and 68 ％.The difference between the two groups were statistically significance (P ＜ 0.05).Conclusions Probiotics treatment neonatal feeding intolerance can reduce the symptoms of vomiting,abdominal distension,promote the recovery of enteral nutrition,shorten the course of the disease,curative effect,which is worth clinical promotion.