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Simultaneous inhibition of DNA methyltransferase and histone deacetylase induces p53-independent apoptosis via down-regulation of Mcl-1 in acute myelogenous leukemia cells |
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| Authors: | Nishioka Chie Ikezoe Takayuki Yang Jing Udaka Keiko Yokoyama Akihito |
| Affiliation: | a Department of immunology, Kochi Medical School, Kochi University, Nankoku, Kochi, Japan b The Japanese Society for the Promotion of Science, Chiyoda-ku, Tokyo, Japan c Department of Hematology and Respiratory Medicine, Kochi University, Oko-cho, Nankoku, Kochi 783-8505, Japan |
| Abstract: | |
| Keywords: | AML, acute myelogenous leukemia DNMTI, DNA methyltransferase inhibitor HDACI, histone deacetylase inhibitor APL, acute promyelocytic leukemia |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |