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Potentielle Reaktivatoren der Acetylcholinesterase 2. Mitt.: Bisquartäre N-Alkoxypyridinium-carbaldoxime
Authors:J Schnekenburger
Abstract:Potential Reactivators of Acetylcholine Esterase. Part 2 Salts of bis(hydroximinomethylpyridiniooxy)-alkanes (BA) are synthesized by alkylation of pyridine-N-oxide-carbaldoximes with bisesters of electronegatively substituted arylsulfonic acids in the presence of DMSO. pKa's, UV-, IR-, and NMR-spectra are discussed, especially with respect to configuration assignments of the oxime functions.
Keywords:
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