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| 滨蒿的化学成分 | |
| 引用本文： | 罗群会,王乃利,刘宏伟,范明,丁爱石,姚新生. 滨蒿的化学成分[J]. 沈阳药科大学学报, 2006, 23(8): 492-494,500 |
| 作者姓名： | 罗群会 王乃利 刘宏伟 范明 丁爱石 姚新生 |
| 作者单位： | 1. 沈阳药科大学,中药学院,辽宁,沈阳,110016 2. 深圳市创新药物研究重点实验室,广东,深圳,518055 3. 军事医学科学院,基础医学研究所,北京,100850 |
| 基金项目： | 致谢：本课题在深圳中药及天然药物研究中心完成,核磁数据和由该中心靳三林测定,质谱数据由该中心王新峦测定. |
| 摘 要： | 目的进一步研究菊科植物滨蒿(Artemisia scoparia)中的化学成分。方法采用硅胶柱色谱法、中低压柱色谱法、ODS柱色谱法、Sephadex LH 20柱色谱法以及高效液色谱法进行分离和纯化,并依据理化性质和波谱解析鉴定其化学结构。结果从植物滨蒿地上部分的体积分数为60%乙醇提取物(420 g)中分得6个化合物,分别鉴定为3羟基二十二酸2(5乙酰基2,3二氢苯并呋喃2基)丙酯(1)、2′(3′甲氧基3甲基丁烯基)对甲氧基乙酰苯(2)、5,8二甲氧基6,7亚甲二氧基香豆素(3)、8甲氧基6,7亚甲二氧基香豆素(4)、6去甲氧基茵陈色原酮(5)、2,4二羟基6甲氧基乙酰苯(6)。结论化合物1~6均为首次从该植物中得到,其中化合物1、2为新化合物。 |
| 关 键 词： | 滨蒿 菊科 化学成分 |
| 文章编号： | 1006-2858（2006）08-0492-03 |
| 收稿时间： | 2005-12-08 |
| 修稿时间： | 2005-12-08 |
Chemical constituents from Artemisia scoparia |
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| LUO Qun-hui,WANG Nai-li,LIU Hong-wei,FAN Ming,DING Ai-shi,YAO Xin-sheng. Chemical constituents from Artemisia scoparia[J]. Journal of Shenyang Pharmaceutical University, 2006, 23(8): 492-494,500 | |
| Authors: | LUO Qun-hui WANG Nai-li LIU Hong-wei FAN Ming DING Ai-shi YAO Xin-sheng |
| Affiliation: | 1. School of Traditional Chinese Maretia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China; 2. Key lab for Research and Development of New Drugs, Shenzhen 518055, China; 3. Institute of Basic Medical Sciences, Academy of Military Medical Sciences, Beijing 100850, China |
| Abstract: | Objective To study the constituents from the aerial parts of Artemisia scoparia.Methods The compounds 1～6 were isolated by a combination of silica gel,Sephadex LH-20,ODS chromatography,and their structures were identified by spectral methods.Results Six compounds were isolated from the aerial parts of Artemisia scoparia.Their structures were established by spectral methods and identified as:2-(5-acetyl-2,3-dihydro-benzofuran-2-yl)-propyl ester(1),2-(3′-methoxyl-3′-methyl-trans-but-1′-enyl)-p-methoxylacetophenone(2),5,8-dimethoxy-6,7-methylenedioxycoumarin(Artemicapin A)(3),8-methoxy-6,7-methylenedioxycoumarin(4),6-demethoxycapillarisin(5),2,4-dihydroxy-6-methoxy-acetophenone(6).Conclusions Compounds 1～6 are firstly isolated from this plant.Compounds 1 and 2 are new compounds. |
| Keywords: | Arternisia scoparia compositae constituents |
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