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络石藤化学成分的研究
引用本文:袁珊琴,于能江,赵毅民,徐斌,姚志伟.络石藤化学成分的研究[J].中草药,2010,41(2):179-181.
作者姓名:袁珊琴  于能江  赵毅民  徐斌  姚志伟
作者单位:军事医学科学院毒物药物研究所,北京,100850
基金项目:国家重大新药创制重大专项(2009ZX0931-002)
摘    要:目的研究络石藤Trachelosperomum jasminoides的化学成分。方法采用色谱技术进行分离纯化,根据波谱学数据鉴定结构。结果从络石藤中分离得到4个单体化合物,分别鉴定为4-二甲基庚二酸(1)、东莨菪素(2)、去甲络石苷元-8-O-β-D-葡萄糖苷(3)及芹菜素-7-O-新橙皮糖苷(4)。结论化合物1为新化合物,化合物2为首次从该植物中分得。

关 键 词:络石藤  4-二甲基庚二酸  东茛菪素  
收稿时间:2009/8/28 0:00:00

Chemical constituents from Trachelosperomum j asminoides
YUAN Shan-qin,YU Neng-jiang,ZHAO Yi-min,XU Bin and YAO Zhi-wei.Chemical constituents from Trachelosperomum j asminoides[J].Chinese Traditional and Herbal Drugs,2010,41(2):179-181.
Authors:YUAN Shan-qin  YU Neng-jiang  ZHAO Yi-min  XU Bin and YAO Zhi-wei
Institution:YUAN Shan-qin,YU Neng-jiang,ZHAO Yi-min,XU Bin,YAO Zhi-wei(Institunte of Pharmacology , Toxicology,Academy of Military Medical Science,Beijing 100850,China)
Abstract:Objective To study the chemical constituents of Trachelosperomum jasminoides. Methods Chromatographic methods were used for the isolation and purification. Structures were elucidated on the basis of spectroscopic data. Results Four compounds were isolated from T. jasminoides and identified as 4-dimethyl heptanedioic acid (1), scopoletin (2), nortrachelogenin-8-O-β-D-glucopyranoside (3), and api-genin-7-O-neohesperidoside (4). Conclusion Compound 1 is a new compound and compound 2 is found in this plant for the first time.
Keywords:Trachelosperomum jasminoides(Lindl  ) Lem    4-dimethyl heptanedioic acid  scopoletin  
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