Müllerian duct anomalies and their effect on the radiotherapeutic management of cervical cancer |
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| Authors: | Madhup Rastogi Swaroop Revannasiddaiah Pragyat Thakur Priyanka Thakur Manish Gupta Manoj K Gupta Rajeev K Seam |
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| Institution: | Madhup Rastogi(Department of Radiotherapy&0ncology, Regional Cancer Centre, Shimla, Himachal Pradesh 171001, India)；Swaroop Revannasiddaiah(Department of Radiation 0ncology, HCG-Bangalore Institute of 0ncology, Bengaluru, Karnataka 560027, India)；Pragyat Thakur(Department of Radiotherapy&0ncology, Regional Cancer Centre, Shimla, Himachal Pradesh 171001, India)；Priyanka Thakur(Department of Radiotherapy&0ncology, Regional Cancer Centre, Shimla, Himachal Pradesh 171001, India)；Manish Gupta(Department of Radiotherapy&0ncology, Regional Cancer Centre, Shimla, Himachal Pradesh 171001, India)；Manoj K. Gupta(Department of Radiotherapy&0ncology, Regional Cancer Centre, Shimla, Himachal Pradesh 171001, India)；Rajeev K. Seam(Department of Radiotherapy&0ncology, Regional Cancer Centre, Shimla, Himachal Pradesh 171001, India)； |
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| Abstract: | Radiotherapy plays a major role in the treatment of cervical cancer. A successful radiotherapy program integrates both external beam and brachytherapy components. The principles of radiotherapy are strongly based on the anatomy of the organ and patterns of local and nodal spread. However, in patients with distorted anatomy, several practical issues arise in the delivery of optimal radiotherapy, especially with brachytherapy. Müllerian duct anomalies result in congenital malformations of the female genital tract. Though being very commonly studied for their deleterious effects on fertility and pregnancy, they have not been recognized for their potential to interfere with the delivery of radiotherapy among patients with cervical cancer. Here, we discuss the management of cervical cancer among patients with Mül erian duct anomalies and review the very sparse amount of published literature on this topic. |
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