从脾论治2型糖尿病伴高同型半胱氨酸血症的临床研究

目的：观察从脾论治2型糖尿病伴高同型半胱氨酸（Hcy）血症的临床疗效。方法：将200例2型糖尿病伴高（Hcy）血症患者采用随机数字表法随机分为治疗组和对照组。两组均采用饮食控制、运动治疗及胰岛素联合口服药物控制血糖。对照组在此基础上给予叶酸片15mg/d，口服；治疗组在此基础上服用中药，1剂/d，分2次口服。两组均以15d为1个疗程，共治疗2个疗程。结果：两组有效率比较，治疗组的疗效明显优于对照组，差异有统计学意义（P〈0.05）。两组空腹 C 肽对比，两组治疗后C肽水平较治疗前显著下降（P〈0.01），两组间比较治疗组优于对照组（P〈0.05）。两组（Hcy）对比，两组治疗后（Hcy）水平较治疗前显著下降（P〈0.01），两组间比较治疗组优于对照组（P〈0.05）。两组胰岛素抵抗指数（HOMAIR）对比，两组治疗后胰岛素抵抗指数较治疗前显著下降（P〈0.05），两组间比较治疗组明显优于对照组（P〈0.01）。结论：从脾论治2型糖尿病伴高（Hcy）血症，在改善症状，恢复胰岛功能，降低（Hcy）方面比西药疗效显著。

Clinical research on treating diabetes2 with high homocysteine

Objective： To observe the clinical efficacy of TCM on treating diabetes 2 with high homocysteine （Hcy） hyperlipidemia. Methods： 200 patients were randomly divided into treatment group and control group. Both groups were given diet, exercise and insulin therapy plus oral medications to control blood sugar. The control group was given folic acid tablets more; the treatment was given TCM medicine more. Results： The efficiency in treatment group was better, the difference was statistically significant （P〈0.05）. C-peptide levels, Hcy and insulin resistance index （HOMAIR） in treatment group were obviously better （P〈0.01）. Conclusion： Treating diabetes 2 in TCM can improve symptoms, restore islet function and reduce Hcy, were better than western medicine.