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恩替卡韦联合水飞蓟宾对慢性乙型病毒性肝炎患者肝功能及肝纤维化指标的影响
引用本文:陈强,贺欢,李粤平,张健珍. 恩替卡韦联合水飞蓟宾对慢性乙型病毒性肝炎患者肝功能及肝纤维化指标的影响[J]. 临床医学工程, 2021, 0(4): 457-458
作者姓名:陈强  贺欢  李粤平  张健珍
作者单位:广州市第八人民医院感染科ICU;广东省妇幼保健院新生儿ICU;广州市第八人民医院肝病科
摘    要:目的 探讨恩替卡韦联合水飞蓟宾对慢性乙型病毒性肝炎患者肝功能及肝纤维化的影响.方法 200例慢性乙型病毒性肝炎患者依据治疗方式的不同分为两组各100例,观察组使用恩替卡韦联合水飞蓟宾治疗,对照组使用恩替卡韦治疗,比较两组的肝功能和肝纤维化指标.结果 治疗6个月后,两组的ALT、TBil、AST、HA、IVC、LN水平均...

关 键 词:慢性乙型病毒性肝炎  恩替卡韦  水飞蓟宾  肝功能  肝纤维化

Impact of Entecavir Combined with Silybinin on Liver Function and Hepatic Fibrosis Indicators of Patients with ChronicViral Hepatitis B
CHEN Qiang,HE Huan,LI Yueping,ZHANG Jianzhen. Impact of Entecavir Combined with Silybinin on Liver Function and Hepatic Fibrosis Indicators of Patients with ChronicViral Hepatitis B[J]. Medical and Health Care Instruments, 2021, 0(4): 457-458
Authors:CHEN Qiang  HE Huan  LI Yueping  ZHANG Jianzhen
Affiliation:(ICU of Infectious Disease Department,Guangzhou Eighth People's Hospital,Guangzhou 510060,China;Neonatal ICU,Guangdong Provincial Maternal and Child Health Hospital,Guangzhou 510010,China;Department of Hepatology,Guangzhou Eighth People's Hospital,Guangzhou 510060,China)
Abstract:Objective To explore the impact of entecavir combined with silybinin on liver function and hepatic fibrosis of patients with chronic viral hepatitis B.Methods 200 patients with chronic viral hepatitis B were divided into two groups according to different treatment methods,with 100 cases in each group.The observation group was treated with entecavir combined with silybinin,and the control group was treated with entecavir.The liver function and liver fibrosis indicators were compared between two groups.Results After 6 months of treatment,the levels of ALT,TBil,AST,HA,IVC and LN in both groups were significantly lower than those before treatment,and the observation group was significantly lower than the control group(P<0.05).Conclusions Entecavir combined with silybinin in the treatment of patients with chronic viral hepatitis B can effectively alleviate liver fibrosis injury and improve liver function.
Keywords:Chronic viral hepatitis B  Entecavir  Silybinin  Liver function  Hepatic fibrosis
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