超声乳化白内障吸除术对老年闭角型青光眼患者血液流变学的影响

目的 探讨利用超声乳化白内障吸除术治疗老年闭角型青光眼患者前后血流动力学变化及治疗效果的影响。方法 86例老年闭角型青光眼患者，随机分为对照组(n=43)和干预组(n=43),并分别进行小梁切除、超声乳化白内障吸除手术治疗。观察分析两组患者的眼压、血液流变学指标，及其与视力、并发症发生率、前房深度、房角黏连闭合等治疗疗效相关性。结果 治疗前，两组患者的视力及眼压，血浆黏度、红细胞压积及血小板黏附率，前房深度及房角黏连闭合度，均没有显著性差异(P>0.05);治疗后，与对照组相比，干预组视力升高(P<0.05),且眼压降低(P<0.05),并发症发生率降低(P<0.05),血浆黏度、红细胞压积及血小板黏附率等指标均明显降低(P<0.05),前房深度及房角黏连闭合度改善程度均明显提高(P<0.05),治疗疗效明显提高(P<0.05)。结论 老年闭角型青光眼患者接受超声乳化白内障吸除术治疗可有效增强治疗疗效，使并发症发生率进一步降低，并促进患者眼压及视力改善，使患者前房深度及血流动力学稳定性显著提升，并能对房角黏连闭合进行有效控制，在老年青光眼治疗中...

Effects of Phacoemulsification and Cataract Extraction on Hemorheology in Patients with Senile Angle-Closure Glaucoma

Objective To investigate the hemodynamic changes and therapeutic effects of phacoemulsification and cataract extraction before and after treatment in patients with senile angle-closure glaucoma (ACG). Methods A total of 86 patients with senile ACG were randomly divided into control group ( n = 43) and experiment group (n= 43), and treated with trabeculectomy and phacoemulsification, respectively. For patients in both groups, the intraocular pressure ( IOP) and hemorheology, and their correlation with visual acuity, incidence of complica- tions, anterior chamber depth, and angle adhesion closure were observed and analyzed. Results Before treatment, there were no significant differences in visual acuity and IOP, plasma viscosity, hematocrit and platelet adhesion rate, anterior chamber depth and angle adhesion closure for patients in both groups (P>0. 05). After treatment, compared with the control group, the experiment group showed higher visual acuity (P<0. 05) and lower IOP ( P < 0. 05), lower incidence of complications ( P < 0. 05), as well as lower plasma viscosity,1039 hematocrit and platelet adhesion rate (P<0. 05). The anterior chamber depth and angle adhesion closure of the experiment group were significantly improved (P<0. 05), and the therapeutic effect was significantly higher (P< 0. 05). Conclusions Phacoemulsification and cataract extraction can effectively enhance the therapeutic effect for patients with senile ACG, further reduce the incidence of complications, promote the improvement of IOP and visual acuity, significantly improve anterior chamber depth and hemodynamic stability, effectively control angle adhesion closure, which can be promoted in the treatment for patients with senile ACG.