| 己酮可可碱葡萄糖注射液内毒素检测法探讨 |
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| 引用本文： | 黄能明,李应锐.己酮可可碱葡萄糖注射液内毒素检测法探讨[J].药学实践杂志,2004,22(1):24-25. |
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| 作者姓名： | 黄能明 李应锐 |
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| 作者单位： | 武警海南省总队医院,海南,海口,570203 |
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| 摘 要： | 目的 :探讨细菌内毒素法对己酮可可碱葡萄糖注射液进行检测的可行性。方法 :按照《中国药典》2 0 0 0版收载的细菌内毒素检查法的要求进行干扰试验。结果 :将己酮可可碱葡萄糖注射液稀释 2倍后对鲎试剂凝集反应没有干扰作用 ,用标示灵敏度为 0 .2 5EU/mL的鲎试剂检测细菌内毒素是有效的。结论 :细菌内毒素法可用于己酮可可碱葡萄糖注射液的检测 ,控制其质量
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| 关 键 词： | 己酮可可碱葡萄糖注射液 细菌内毒素检查法 鲎试剂 |
| 文章编号： | 1006-0111(2004)01-0024-02 |
| 收稿时间： | 2003/8/29 0:00:00 |
| 修稿时间： | 2003年8月29日 |
Study on BET in pentoxifylline glucose injection |
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| HUANG Neng-ming and LI Ying-rui.Study on BET in pentoxifylline glucose injection[J].The Journal of Pharmaceutical Practice,2004,22(1):24-25. |
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| Authors: | HUANG Neng-ming and LI Ying-rui |
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| Institution: | Hainan Provincial Corps Hospital, Chinese People's Armed Polices Forces, Haikou 570203, China;Hainan Provincial Corps Hospital, Chinese People's Armed Polices Forces, Haikou 570203, China |
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| Abstract: | Objective: To study the feasibility of bacterial endotoxin test(BET) for the pentoxifylline glucose injection.Methods: The interference test was conducted with reference to Chinese Pharmacopoeia(2000ed) on BET.Results: The tachypleus amebocyte lysate has no interfered by the pentoxifylline glucose injection diluted 2 times in the coagulate reaction, so it is valid to use the sensitivity of TAL 0.25EU/mL to test bacterial endotoxin. Conclusion:The bacterial endotoxin test(BET) can be used as quality control of the pentoxifylline glucose injection. |
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| Keywords: | pentoxifylline glucose injection bacterial endotoxin test tachypleus amebocyte lysate |
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