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小学生乙型肝炎疫苗免疫效果观察
引用本文:张留寿,吴淑华,黄灵,朱桂芳,肖美,钱霞,徐华.小学生乙型肝炎疫苗免疫效果观察[J].现代预防医学,2004,31(2):219-220.
作者姓名:张留寿  吴淑华  黄灵  朱桂芳  肖美  钱霞  徐华
作者单位:江苏省泰兴市卫生防疫站,泰兴,225400
摘    要:目的 :研究乙型肝炎疫苗接种后小学生中抗 HBs的水平。方法 :对城区 7所小学利用整群随机抽样方法进行乙肝疫苗免疫效果的检测。结果 :接种乙肝疫苗 7年的抗 - HBs阳性率达 6 5 .98% ,12年达 38.31%。其免疫保护率为 73.0 0 %。各年级间免疫率差异有非常显著性 ,并且抗体水平随着年龄 (时间 )的增加而慢慢消失 ,乙肝疫苗注射后使儿童 HBs Ag感染率由 7.4 %下降到 2 .0 %。结论 :为提高乙肝疫苗的免疫效果 ,必须 7岁时开始乙肝疫苗加强接种

关 键 词:乙型肝炎疫苗  免疫效果  乙型肝炎表面抗原  乙型肝炎表面抗体
文章编号:1003-8507(2004)02-0219-02
修稿时间:2003年6月17日

THE STUDY ON EFFECT OF IMMUNOREACTION OF HEPATITIS B VACCINE ON PUPILS
ZHANG Liu-shou,WU Shu-hua,HUANG ling,et al..THE STUDY ON EFFECT OF IMMUNOREACTION OF HEPATITIS B VACCINE ON PUPILS[J].Modern Preventive Medicine,2004,31(2):219-220.
Authors:ZHANG Liu-shou  WU Shu-hua  HUANG ling  
Institution:ZHANG Liu-shou,WU Shu-hua,HUANG ling,et al.Taixing Health and Anti-epidemic Station Taixing in Jiangsu Province,Taixing,225400.
Abstract:Objective:To investigate the effect of immunoreaction of hepatitis B vaccine on pupils.Methods:A randomized sampling survey was carried out.A total number of 2770 pupils were selected in the city.Results:The effect of the hepatitis B vaccination was satisfactory,the rate of protection was 73.0%.There was a significant difference among the rate of immune of every grade.The carrier rate of HBsAg decreased from 7.4% to 2.0% in children who were vaccinated.Postitive rates of anti-HBs were 65.98?ter 7 years and postitive rates of anti-HBs were 38.31% after 12 years.Conclusion:It suggests that hepatitis B vaccination was one of the ways that can prevent in fection of HBsAg.It is necessary to provide hepatitis B vaccines to children when they are 7 years old.
Keywords:Hepatitis B vaccines  Immunoreaction  HBsAg  Anti-HBs
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