| 变应性鼻炎患者可溶性白细胞介素-2受体的测定 |
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| 引用本文： | 李添应,李妮娜,邱前辉,郭洁波,陈炳生. 变应性鼻炎患者可溶性白细胞介素-2受体的测定[J]. 中华耳鼻咽喉头颈外科杂志, 1997, 0(4) |
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| 作者姓名： | 李添应 李妮娜 邱前辉 郭洁波 陈炳生 |
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| 作者单位： | 中山医科大学第一附属医院耳鼻咽喉科，四川重庆钢铁厂职工医院，中山医科大学实验核医学教研室 |
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| 摘 要： | 为探讨可溶性白细胞介素－２受体（ｓｏｌｕｂｌｅｉｎｔｅｒｌｅｕｋｉｎ２ｒｅｃｅｐｔｏｒ，ＳＩＬ－２Ｒ）在变应性鼻炎中的作用机理，采用双抗体夹心酶联免疫吸附测定（ＥＬＩＳＡ）法测定３９例变应性鼻炎患者、１９例慢性鼻炎患者和１５例健康人血清及鼻分泌物ＳＩＬ－２Ｒ水平。结果发现变应性鼻炎患者血清ＳＩＬ－２Ｒ水平高于慢性鼻炎患者及健康人（Ｐ＜０．００１）。提示ＳＩＬ－２Ｒ在变应性鼻炎的发病中起重要作用
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| 关 键 词： | 鼻炎，变应性，常年性受体，白细胞介素－2 |
Determination of soluble interleukin 2 receptor levels in patients with allergic rhinitis |
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| Li Tianying,Li Nina,Qiu Qianhui,et al.. Determination of soluble interleukin 2 receptor levels in patients with allergic rhinitis[J]. Chinese journal of otorhinolaryngology head and neck surgery, 1997, 0(4) |
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| Authors: | Li Tianying Li Nina Qiu Qianhui et al. |
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| Affiliation: | Li Tianying,Li Nina,Qiu Qianhui,et al. First Affiliated Hospital,Sun Yat Sen University of Medical Sciences,Guangzhou 510089 |
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| Abstract: | To explore the regulatory mechanism of the soluble interleukin 2 receptor (SIL 2R) in patient allergic rhinitis, SIL 2R levels in serum and nasal secretion were detected in 39 patients with allergic rhinitis, 19 patients with chronic rhinitis and 15 normal controls, The determination of SIL 2R was done by a sandwich ELISA method. The results showed that the SIL 2R concentrations in patients with allergic rhinitis were significantly higher than those of the controls ( P <0.001). These results suggest that SIL 2R may play an important role in allergic rhinitis. |
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| Keywords: | Rhinitis allergic perennial Receptors interleukin 2 |
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