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Regulation of accumulation and function of myeloid derived suppressor cells in different murine models of hepatocellular carcinoma |
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| Authors: | Tamar Kapanadze Jaba Gamrekelashvili Chi Ma Carmen Chan Fei Zhao Stephen Hewitt Lars Zender Veena Kapoor Dean W. Felsher Michael P. Manns Firouzeh Korangy Tim F. Greten |
| Affiliation: | 1 Gastrointestinal Malignancy Section, Medical Oncology Branch, National Cancer Institute, Bethesda, USA;2 Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany;3 Laboratory of Pathology, National Cancer Institute, NIH, Bethesda, USA;4 Department of Gastroenterology, University of Tübingen, Tübingen, Germany;5 Experimental Transplantation and Immunology Branch, NIH, Bethesda, USA;6 Division of Medical Oncology, Department of Medicine, Stanford University, CA, USA |
| Abstract: | |
| Keywords: | BLR, body weight/liver weight ratio DEN, diethylnitrosoamine G-CSF, granulocyte colony stimulating factor GM-CSF, granulocyte-macrophage colony stimulating factor HCC, hepatocellular carcinoma IL, interleukin iNOS, inducible nitric oxide synthase KC, keratinocyte-derived chemokine LAP, liver activator protein L-NMMA, NG-methyl-L-arginine MCP, macrophage chemotactic protein MDSC, myeloid derived suppressor cell NK, natural killer N-NOHA, Nω-hydroxil-nor-L-arginine OVA, ovalbumin VEGF, vascular endothelial growth factor WT, wild type |
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