Wnt signaling and hepatocarcinogenesis: Molecular targets for the development of innovative anticancer drugs |
| |
| Authors: | Floriane Pez,Anaï s Lopez,Miran Kim,Jack R. Wands,Claude Caron de Fromentel,Philippe Merle |
| |
| Affiliation: | 1 INSERM U1052, CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, F-69008 Lyon, France;2 Université Lyon-1, F-69622 Villeurbanne, France;3 Centre Léon Bérard, F-69008 Lyon, France;4 The Liver Research Center, Brown University, Providence, RI, USA;5 Hospices Civils de Lyon, Service d’Hépatologie et de Gastroentérologie, Groupement Hospitalier Lyon Nord, F-69000 Lyon, France |
| |
| Abstract: | |
| |
| Keywords: | HCC, hepatocellular carcinoma FZD, frizzled CSC, cancer stem cells PCP, planar cell polarity TCF/LEF, T-cell factor/lymphoid enhancer factor TLE-1, transducin like enhancer-1 APC, adenomatous polyposis coli protein GSK3β, glycogen synthase kinase 3β CK1, casein kinase 1 β-TRCP, beta-transducin repeat containing protein SCF, Skp1/cullin F-box complex Dvl/Dsh, disheveled Pygo, pygopus CBP, CREB-binding protein PKC, protein kinase C NFAT, nuclear factor of activated T cell NLK, Nemo-like kinase Wif1, Wnt inhibitory protein-1 sFRP, secreted FZD-related proteins Dkk, Dickkopf Krm, Kremen Rspo, R-spondin Gpc3, glypican-3 DIFs, differentiation-inducing factors |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
