Late functional deterioration following paralytic poliomyelitis |
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Authors: | Kidd D; Howard RS; Williams AJ; Heatley FW; Panayiotopoulos CP; Spencer GT |
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Institution: | Department of Neurology, St Thomas' Hospital, London, UK. |
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Abstract: | Many patients with previous poliomyelitis develop 'post-polio syndrome'
(PPS) in which late functional deterioration follows a period of relative
stability. The frequency with which PPS can be attributed to clearly
defined causes remains uncertain. We reviewed 283 newly- referred patients
with previous poliomyelitis seen consecutively over a 4-year period; 239
patients developed symptoms of functional deterioration at a mean of 35
(5-65) years after the paralytic illness. Functional deterioration was
associated with orthopaedic disorders in 170 cases, neurological disorders
in 35, respiratory disorders in 19 and other disorders in 15. Progressive
post-polio muscular atrophy was not observed. Functional deterioration
following paralytic polio- myelitis is common, and associated with
orthopaedic, neurological, respiratory and general medical factors which
are potentially treatable.
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