尿激酶溶栓治疗心肌梗死80例临床效果评价

目的：探讨尿激酶溶栓治疗心肌梗死的临床疗效；方法：本文对对收治的80例急性心肌梗死患者采用尿激酶溶栓治疗，并与对照组进行临床疗效比较；结果：对照组中再通率为70．0％（56／80），而治疗组的再通率则达到了88．8％（71／80），经统计分析分析发现，治疗组的再通率明显高于对照组（P〈0．05）。结论：采用尿激酶溶栓治疗急性心肌梗死可以明显提高患者的血管再通率，出血不良反应低且无过敏现象等并发症，值得临床推广使用。

Clinical effect appraise of intravenous throbbolysis with urokinase in treating 80 cases with acute myocardial infarction

Objective： to explore the clinical effect of intravenous throbbolysis with urokinase in treating patients with acute myocardial infarction. Method ： select 80 acute myocardial infarction patients that treated in our hospital from March 2004 to July 2009, and randomly divided into observation group and control group, 40 patients in each group, the observation group are treated by throbbolysis with urokinase and the control group are treated with traditional method, compare their treat effect, cardiac events incidence rate and drug side effect. Results： vascular recanalization rate in 90 minutes, 120 minutes and 180 minutes is 52.5% ,67.5% and 77.5%, which of the control group is 17.5% ,32.5 % and 35 % seperatively, the difference is statistical significant （P 〈 0.05 ） ;4 patients of the observation group have relapse angina, 2 patients have unfetal myocardial infarction, cardiac events incidence rate is 15%, while 6 patients of the observation group have relapse angina, 3 patients have unfetal myocardial infarction, 2 patients cardiac death, cardiac events incidence rate is 27.5 %, the difference is statistical significant （ P 〈 0.05 ） ; the difference of the two groups of drug side effect has no sta- tistical significance（ P 〉 0.05 ）. Conclusion： it has good effect to treat myocardial infarction by intravenous throbbolysis with urokinase and can be widely used in clinic.