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Evaluation of intermittent hepatic arterial infusion chemotherapy for multiple liver metastasis of colorectal cancer
Authors:Yoshioka S  Morimoto T  Shingai T  Azama T  Katsumoto Y  Nakaguchi K  Furukawa J  Okajima S  Sue F
Affiliation:Dept. of Surgery, Suita Municipal Hospital.
Abstract:Five patients with synchronous multiple hepatic metastasis of colorectal cancer were treated with hepatic arterial infusion chemotherapy. All cases received intermittent 5-FU infusion (5-FU 250-1,000 mg/2-3 hrs/1-2 weeks) on an outpatient basis. In the evaluation of 5 cases, 3 PR and 1 NC were observed. One case administered arterial infusion for adjuvant chemotherapy has no recurrence in liver. In two patients, extra-hepatic metastases were found. In conclusion, this therapy was effective and useful for hepatic metastasis. Moreover, other forms of treatment for extra-hepatic metastasis must be used.
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