女性泌尿生殖道感染支原体的耐药性监测分析

目的探讨女性泌尿生殖道解脲支原体（uu）和人型支原体（Mh）感染状况及对抗菌药物的敏感性。方法回顾性统计分析2006年1月—2008年12月送检的2090份女性泌尿生殖道分泌物标本支原体培养及药敏试验结果。结果2090份标本中，支原体培养阳性836例，阳性率40．0％，其中21-40岁年龄段女性患者培养阳性率最高。12种常用抗菌药物中，四环素类敏感率最高；大环内酯类敏感率占第2位；4种喹诺酮类药物均呈现较高的耐药率，敏感率均〈50．0％。结论女性泌尿生殖道支原体对抗菌药物的耐药性已非常严重，应引起临床重视。

Resistance Monitoring of Mycoplasma Isolated form Female Genitourinary Tract

Objective]To investigate the Ureaplasma urealyticum (Uu) and Mycoplasma hominis (Mh) infection status in female genitourinary tract and their antimicrobial sensitivity.Methods]A total of 2090 female genitourinary tract specimens were collected from Jan 2006 to Dec 2008 . The results of mycoplasma cultivation and susceptibility test were analyzed retrospectively.Results]Among 2090 specimens, 836 were mycoplasma positive, and the positive rate was 40.0%. The culture positive rate was the highest in 21-40 age group. From 12 commonly used antibiotics, the sensitivity to tetracyclines was the highest, followed by macrolides. All 4 kinds of quinolones showed the higher resistance, and their sensitivity rates were all below 50%.Conclusion]The drug resistance of mycoplasma in female genitourinary tract is greatly severe that clinical doctors should pay more attention to it.