直肠癌直肠系膜全切除术的临床病理依据及意义

目的 探讨直肠癌直肠系膜全切除术的临床病理依据.方法 对102例具有较完整临床病理资料行直肠癌直肠系膜全切除术直肠癌组织、癌旁组织、直肠系膜进行常规病理切片,分析直肠系膜与直肠癌的分化程度、临床分期、淋巴结转移的关系及治疗效果.结果 直肠系膜癌转移均与癌组织分化程度、临床分期、淋巴结转移有相关性(P<0.05).结论 直肠癌直肠系膜全切除术是治疗直肠癌的最佳途径,切除的直肠系膜的范围应根据Dukes分期、肿瘤的分化程度及肿瘤浸润肠壁的深度区别对待.

Clinicopathologic Evidence and the Significance for Total Mesorectal Excision in Rectal Cancer

Objective To discuss the clinicopathologic evidence for total mesorectal excision(TME) in rectal cancer. Methods Tissues of rectal cancer, tissues around the tumor and tissues of the mesorectum were all obtained from 102 patients who proceeded to TME procedure. Pathological sections were performed to analyze the relationship between the state of mesorectum and the differentiation, staging, lym-phadenopathy of rectal cancer, also analyze the effect of treatment. Results There was correlation(P<0.05) between metastasis to mesoreetum and the differentiation, staging, lymphadenopathy of cancer. Conclusions TME was the best of choice for the treatment of rectal cancer. The extent of mesorectum to be excised depended on Dukes staging, differentiation and depth of infiltration of the tumor.