云南省曲靖市631例肺癌患者临床特征分析

目的分析肺癌患者的临床特征,为肺癌的相关预防、诊治提供依据。方法选择云南省曲靖市第二人民医院2015年1月-2018年6月收治的631例肺癌患者作为研究对象,分析所有患者的性别、年龄、地域分布、吸烟史、肺部疾病史、病理类型等临床资料。结果 631例肺癌患者中,有腺癌378例(占59.91%),鳞癌197例(占31.22%),小细胞肺癌44例(占6.97%),其他12例(占1.90%)。肺癌患者男女比例为1.84:1。在鳞癌和小细胞肺癌中,男性所占比例均明显高于女性〔鳞癌:94.42%(186/197)比5.58%(11/197),小细胞肺癌:75.00%(33/44)比25.00%(11/44)〕,差异均有统计学意义(均P<0.01),在腺癌和其他病理分型中,男性和女性所占比例差异均无统计学意义(均P>0.05)。肺癌患者平均发病年龄为(61.95±10.98)岁,男性平均(62.56±10.97)岁,女性平均(60.57±11.66)岁,高发年龄为51~70岁。肺癌患者地域分布为麒麟区(216例)、宣威市(115例)、富源县(98例)、沾益区(81例)最为高发。肺癌患者的吸烟率为46.28%,其中鳞癌、小细胞肺癌患者的吸烟率较高,分别为69.04%、56.82%,腺癌患者吸烟率相对较低,为34.13%。既往有慢性肺部疾病史的肺癌患者共101例,占16.01%。结论云南省曲靖市是云南省肺癌高发地区,分析肺癌患者的临床特征对控制危险因素和促进高风险人群的早期发现具有重要意义。

Clinical characteristics of 631 patients with lung cancer in Qujing City,Yunnan Province

Objective To analyze the clinical characteristics of patients with lung cancer,and provide evidence for prevention,diagnosis,and treatment of lung cancer.Methods The 631 lung cancer patients admitted in Qujing Second People’s Hospital from January 2015 to June 2018 were selected,and the clinical data including gender,age,geographical distribution,smoking history,pulmonary disease history,and pathological type were retrospectively analyzed.Results Among the 631 patients with lung cancer,378 cases were adenocarcinoma,accounting for 59.91%;197 cases were squamous cell carcinoma,accounting for 31.22%;44 cases were small-celllung cancer,accounting for 6.97%;the other 12 cases were adenocarcinoma,accounting for 1.90%.The ratio of male and female was 1.84:1 in lung cancer patients.In squamous cell carcinoma and small cell lung cancer,the proportion of men was significantly higher than that of women squamous cell carcinoma:94.42% (186/197) vs.5.58% (11/197),small cell lung cancer:75.00% (33/44) vs.25.00% (11/44)],with significant difference (both P < 0.01).There was no significant difference in the proportion of men and women in adenocarcinoma and other pathological types (P > 0.05).The average age of lung cancer patients was (61.95±10.98) years old;the average age of male and female was (62.56±10.97) and (60.57±11.66) years old.The geographical distribution of patients with lung cancer was as follows.Qilin (216 cases),Xuanwei (115 cases),Fuyuan (98 cases) and Zhanyi regions (81 cases) were high incidence areas.The smoking rate of 631 lung cancer patinets was 46.28%,among which the smoking rates of patients with squamous cell lung cancer and small cell lung cancer were higher (69.04% and 56.82%,respectively),and the smoking rate of patients with adenocarcinoma was relatively low (34.13%).There were 101 cases with a history of chronic lung disease,accounting for 16.01%.Conclusion Qujing City,Yunnan Province is a high incidence area of lung cancer in Yunnan Province,and the analysis on clinical characteristics of patients with lung cancer has a critical significance on the control of risk factors and improvement of early detection of lung cancer.