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少腹逐瘀汤对寒凝血瘀大鼠模型血液流变性及卵巢功能的影响
引用本文:宿树兰,段金廒,王团结,余黎,华永庆,唐于平.少腹逐瘀汤对寒凝血瘀大鼠模型血液流变性及卵巢功能的影响[J].中国实验方剂学杂志,2008,14(12):41-43.
作者姓名:宿树兰  段金廒  王团结  余黎  华永庆  唐于平
作者单位:1. 南京中医药大学,江苏省方剂研究重点实验室,江苏,南京,210046
2. 江苏大学药学院,江苏,镇江,212013;南京中医药大学,江苏省方剂研究重点实验室,江苏,南京,210046
基金项目:江苏省高校自然科学重大基础研究项目,江苏省青蓝工程科技创新团队建设项目 
摘    要:目的:评价少腹逐瘀汤对寒凝血瘀SD大鼠模型血液流变性及卵巢功能的影响。方法:采用冰水浴及注射肾上腺素的方法造成SD大鼠急性血瘀模型,对其血液流变性及卵巢分泌功能进行测定。结果:少腹逐瘀汤能改善寒凝血瘀SD大鼠血液流变性指标;对卵巢功能也显示出一定改善作用。结论:少腹逐瘀汤能改善寒凝血瘀SD大鼠全血黏度、血浆黏度、血沉、红细胞压积及调节E2和P的水平。

关 键 词:少腹逐瘀汤  寒凝血瘀  血液流变学  卵巢功能
收稿时间:2008/8/12 0:00:00

Evaluating the Effects of Shaofu Zhuyu Decoction on Hemorheology and Ovarian Function in Rat Model of Han-Ning Blood Stasis
SU Shu-lan,DUAN Jin-ao,WANG Tuan-jie.Evaluating the Effects of Shaofu Zhuyu Decoction on Hemorheology and Ovarian Function in Rat Model of Han-Ning Blood Stasis[J].China Journal of Experimental Traditional Medical Formulae,2008,14(12):41-43.
Authors:SU Shu-lan  DUAN Jin-ao  WANG Tuan-jie
Institution:1.Key Laboratory for Modern Research of Traditional Chinese Medicine,Nanjing University of Traditional Chinese Medicine,Nanjing 210046,China;2.Department of Pharmacy,Jiangsu University,Zhenjiang 212013,China
Abstract:Objective:To evaluate the effects of Shaofu Zhuyu decoction(SFZYD) on hemorheology and ovarian function in rat mode of Han-Ning blood stasis.Methods: The method of ice water bath combined with injection of adrenalin was adopted to established cold stagnation and blood stasis in rats.The indexes of hemorheology and E2 and P were detected.Result: The results stated that SFZYD and ethanol supernatant showed significant improvements in the hemorheological indexes of rats in the model of blood stasis and regulation for the secret function on rat ovarian.Conclusion: SFZYD can improve the indexes of hemorheology in rat model of blood stasis and regulate the secretion of E2 and P.
Keywords:Shaofu Zhuyu Decoction  cold stagnation and blood stasis  hemorheology  ovarian function
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