原发性IgA肾病113例牛津病理分型研究

目的 探讨IgA肾病新型评价标准--"牛津病理分型"与以往评价系统的相关性,以加深对此新型评价标准的认识.方法 对113例经肾活检确诊的原发性IgA肾病患者的病理资料分别按照改良HS Lee分级标准及IgA肾病牛津分型标准进行评价.结果 IgA肾病牛津病理分型与改良HS Lee分级标准间有相关性(P＜0.05).结论 IgA肾病牛津病理分型标准继承了以往评价标准的优势,而且可以更全面的评价病理资料,但新型评价标准尚存在一定的局限性,需进一步完善及更大样本的资料研究验证.

Oxford pathological typing of primary IgA nephropathy: a study of 113 cases

Purpose To discuss the relevance of "Oxford pathological type" which is a new evaluation system of IgA nephropathy and the previous evaluation system,for deepening the understanding of the new evaluation criteria.Methods The pathological data of 113 patients with primary IgA nephropathy diagnosed by renal biopsy were evaluated by modified HS Lee grading standards and Oxford pathological type.Results There was correlation between IgA nephropathy Oxford pathological type and modified HS Lee grading standards(P<0.05).Conclusions Oxford pathological classification of IgA nephropathy not only inherits the advantages of the previous evaluation criteria,but also evaluates the pathological data more comprehensively.However,there are still some limitations of the new evaluation criteria needed to be further improved and tested by large-scale research.