| 大肠癌及其癌前病变AgNORs的研究 |
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| 引用本文： | 张浩波 郁宝铭. 大肠癌及其癌前病变AgNORs的研究[J]. 上海交通大学学报(医学版), 1995, 15(1): 24-27 |
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| 作者姓名： | 张浩波 郁宝铭 |
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| 作者单位： | 上海第二医科大学附属瑞金医院外科 |
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| 摘 要： | 应用自动图象分析仪，对６５例大肠癌和伴不同程度不典型增生的大肠腺瘤以及正常肠粘膜的标本，进行了ＡｇＮＯＲｓ颗粒数和颗粒面积的测定和分析。研究认为：ＡｇＮＯＲｓ测定可作为大肠癌及其癌前病变的客观诊断指标，大肠重度不典型增生和癌有较我相似特性，上对此病变要高度警惕。
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| 关 键 词： | 大肠肿瘤 腺癌 癌前病变 AgNOR染色 |
AgNORs Study of Colorectal Cancer and Precancerous Lesions |
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| Zhang Haobo,et al. AgNORs Study of Colorectal Cancer and Precancerous Lesions[J]. Journal of Shanghai Jiaotong University:Medical Science, 1995, 15(1): 24-27 |
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| Authors: | Zhang Haobo et al |
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| Abstract: | Specimens taken from the normal mucosa,adenoma associated with varied degrees of dysplasia and colorectal adenocarcinoma 65 cases were submitted to AgNORs stuey with an automatic image analysis system.Results showed that the mean number of AgNORs per nucleus increased with exaggeration of cell atypia,while the mean area per AgNORs granule decreased.Differences between different groups were statistically significant (P<0.01).We concluded that the measurement of AgNORs can act as an objective diag nostic criteria to colorectal tumours and severe dysplasia has close resemblance to cancer,suggesting precantions should be paid. |
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| Keywords: | colorectal cancer dyplasia AgNORs colorectal adenoma |
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