Variables of patient-controlled analgesia 1. bolus size |
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Authors: | H. OWEN J. L. PLUMMER I. ARMSTRONG L. E. MATHER M. J. COUSINS |
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Affiliation: | Department of Anaesthesia and Intensive Care Flinders University of South Australia, Bedford Park. |
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Abstract: | The efficacy of a range of demand doses of morphine for patient-controlled analgesia was studied. Patients who self-administered the smallest dose (0.5 mg) were frequently unable to achieve good pain control; patients who received the largest dose (2 mg) had a high incidence of ventilatory depression. A dose of 1 mg was the best increment under the conditions of this study but the relationship between increment and lockout interval requires consideration. |
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Keywords: | Pain postoperative Analgesia on-demand |
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