| 反向疫苗学:恶性疟疫苗研制新策略 |
| |
| 引用本文： | 熊美燕,董莹.反向疫苗学:恶性疟疫苗研制新策略[J].国际医学寄生虫病杂志,2009,36(4):227-231. |
| |
| 作者姓名： | 熊美燕 董莹 |
| |
| 作者单位： | 1. 大理学院病原与媒介生物研究所,671000
2. 671000,大理学院病原与媒介生物研究所;665000普洱,云南省寄生虫病防治所 |
| |
| 摘 要： | 基因组技术和生物信息学的发展催生了反向疫苗学,它是从全基因组水平筛选保护性免疫抗原的新方法.疟疾主要由4种人体疟原虫引起.恶性疟原虫14条染色体上的全基因组序列测定目前已经完成,因此,利用反向疫苗技术研制恶性疟候选疫苗将是有效的新策略.
|
| 关 键 词： | 反向疫苗学 候选抗原 恶性疟 基因组 |
Reverse vaccinology: a new strategy to develop falciparum malaria vaccine |
| |
| XIONG Mei-yan,DONG Ying.Reverse vaccinology: a new strategy to develop falciparum malaria vaccine[J].International JOurnal of Medical Parasitic Diseases,2009,36(4):227-231. |
| |
| Authors: | XIONG Mei-yan DONG Ying |
| |
| Abstract: | Genome technology and bioinformatics lead to the development of reverse vaceinology, which is a new method of screening the protective immunity antigen from the whole genome level. Malaria is mainly caused by four species of human Plasmodium parasites. The work of sequencing genome on 14 chromo-somes of Plasmodiumfalciparum has been completed. Therefore, studying on Plasmodiumfalciparum candidate vaccine with reverse vaccine technology will become a new effective strategy. |
| |
| Keywords: | Reverse vaecinologyCandidate antigenPlasmodiumfalciparumGenome |
| 本文献已被 万方数据 等数据库收录！ |
|
