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川崎病患儿血浆心钠素心指数的观察
引用本文:张双船,江迅,裴群,叶静平,田琳,江钟炎,麦根荣.川崎病患儿血浆心钠素心指数的观察[J].武汉大学学报(医学版),1998(3).
作者姓名:张双船  江迅  裴群  叶静平  田琳  江钟炎  麦根荣
作者单位:Department of Pediatric,First Affiliated Hospital,Hubei Medical University,Wuhan 430060,China
摘    要:对22例川崎病患儿血浆心钠素(ANP)、心指数(CI)的临床观察结果表明:川崎病患儿在其病程的急性期血浆ANP浓度明显高于对照组(P<0.05),CI明显下降(P<0.05)。血浆ANP浓度和CI之间呈负相关(r=-0.612,P<0.05)。17例未并发动脉瘤的患儿在临床症状消退后ANP和CI基本恢复正常。但5例并发动脉瘤的病例ANP浓度和CI异常则持续很长时间。初步认为:川崎病患儿血浆ANP浓度的测定可以帮助我们了解川崎病患儿的心脏功能,对预后的评价有一定帮助

关 键 词:心钠素  心指数  粘膜皮肤淋巴结综合征

A Clinic Study of Plasma Atrial Natriuetic Polypeptid in the Children with the Mucocutaneous Lymphnode Syndrome
Zhang Shuangchuan,Jiang Xun,Pei Qun,et al.A Clinic Study of Plasma Atrial Natriuetic Polypeptid in the Children with the Mucocutaneous Lymphnode Syndrome[J].Medical Journal of Wuhan University,1998(3).
Authors:Zhang Shuangchuan  Jiang Xun  Pei Qun  
Abstract:mucocutaneous lymphnode syndrome patients were studied with their plasma natriuretic polypeptide (ANP) and cardiac index (CI). The results show that the patients when in the acute phase have a significant higher plasma ANP concentration and significant lower CI ( P <0.05). As for 17 without coronary aneurysm, when their illness was cured their pANP and CI went normal. But as for the other 5 with coronary aneurysm their higher pANP level lasted over 6 months. So the pANP laboratory assay might help us to know the patients’ cardiac function and if the patient has a coronary aneurysm
Keywords:atrial natriuretic factor  cardiac index  mucocutaneous lymph node syndrome
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