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Combined approaches for the relief of spinal cord injury-induced neuropathic pain
Affiliation:1. Department of Chinese Medicine, China Medical University Hospital, Taichung 404, Taiwan;2. School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung 404, Taiwan;3. Research Center for Traditional Chinese Medicine, Department of Medical Research, China Medical University Hospital, Taichung 404, Taiwan;4. Research Center for Chinese Herbal Medicine, China Medical University, Taichung 404, Taiwan;5. Chinese Medicine Research Center, China Medical University, Taichung 404, Taiwan;6. Department of Biotechnology, Asia University, Taichung 413, Taiwan;7. Management Office for Health Data, China Medical University Hospital, Taichung 404, Taiwan;8. Graduate Institute of Acupuncture Science, College of Chinese Medicine, China Medical University, Taichung 404, Taiwan
Abstract:The adequate treatment of spinal cord injury (SCI)-induced neuropathic pain still remains an unresolved problem. The current medications predominantly used in the SCI-induced neuropathic pain therapy are morphine, anticonvulsants, antidepressants, and antiepileptics, which suggests that psychiatric aspects might be important factors in the treatment of neuropathic pain.It is well documented that the modulation of the sensory events is not a unique way for achieving pain relief. In addition, pain patients still express dissatisfaction and complain of unwanted effects of the medications, suggesting that alternative approaches for the treatment of neuropathic pain are essential. In psychiatry, pain relief represents relaxation and a feeling of comfort and satisfaction, which suggests that cognitive and emotional motivations are important factors in the treatment of neuropathic pain. The comorbidity of chronic pain and psychiatric disorders, which is well recognized, suggests that the effective therapeutic relief for neuropathic pain induced by SCI can be achieved in conjunction with the management of the sensory and psychiatric aspects of patient.In this review, we address the feasibility of a combined acupuncture and pharmacotherapy treatment for the relief of neuropathic pain behavior following SCI.
Keywords:Acupuncture  GABA  Neuropathic pain  Reward  Spinal cord injury
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