酚妥拉明治疗慢性肺源性心脏病心衰的临床观察

目的观察酚妥拉明对慢性肺源性心脏病心衰患者的疗效,为临床治疗提供依据。方法将70例患者随机分为治疗组和对照组各35例。两组采用常规内科治疗如控制感染、氧疗、强心、利尿等,治疗组在上述治疗基础上加用酚妥拉明10mg加入生理盐水50ml中微泵静脉推注（5ml/h）,1次/d,疗程均为10d。结果治疗组的疗效、临床症状、血气分析及心功能的改善优于对照组,差异具有统计学意义（P〈0.05）。结论酚妥拉明对慢性肺源性心脏病心衰患者具有良好的疗效及安全性,值得临床推广应用。

The clinical observation of phentolamine in the treatment of chronic pulmonary heart disease with heart failure

Objective To observed the clinical effect of phentolamine in the treatment of chronic pulmonary heart disease with heart failure. Methods 70patients were randomly divided into control group （ n = 35） and therapy group（ n = 35）. Two groups were treated with medical treatment,such as control infection、oxygen therapy、cardiotonic、diuresis. On the basis of the above therapy,the treatment group add phentolamine 10 mg with normal saline 50 ml in micro-pump intravenous injection （ 5 ml / h） ,quotidie,10 days for a course of treatment. Results Compare with the control group,the therapeutic effect 、clinical symptoms、blood gas analysis、heart function in therapy group were significant difference（ P〈 0. 05）. Conclusion Phentolamine in the treatment of chronic pulmonary heart disease with heart failure is effective and safe. It deserves to be popularized.