| 慢性肾炎患者输注红细胞前后SF、血清VEGF和HGF水平及临床意义 |
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| 引用本文： | 穆培栋,何浩明.慢性肾炎患者输注红细胞前后SF、血清VEGF和HGF水平及临床意义[J].放射免疫学杂志,2011,24(6):642-644. |
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| 作者姓名： | 穆培栋 何浩明 |
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| 作者单位： | 1. 连云港市中心血站
2. 连云港市第一人民医院 |
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| 摘 要： | 目的:探讨了慢性肾炎患者在输注红细胞前后血清铁蛋白(SF)、血管内皮生长因子(VEGF)和肝细胞生长因子(HGF)水平的变化及意义.方法:应用放射免疫分析和酶联法对30例慢性肾炎患者进行了输注红细胞前后SF、血清VEGF和HGF检测,并与35名正常健康人作比较.结果:慢性肾炎患者在输注红细胞前SF水平非常显著地低于正常...
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| 关 键 词： | 慢性肾炎 血清铁蛋白 血管内皮生长因子 肝细胞生长因子 |
Clinical Significance of Estimation of Changes in Serum SF,VEGF and HGF Levels and After Transfusion of Red Blood Cells in Patients with Chronic Nephritis |
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| Mu Pei-dong,He Hao-ming.Clinical Significance of Estimation of Changes in Serum SF,VEGF and HGF Levels and After Transfusion of Red Blood Cells in Patients with Chronic Nephritis[J].Journal of Radioimmanology,2011,24(6):642-644. |
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| Authors: | Mu Pei-dong He Hao-ming |
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| Institution: | 1 Lianyungang Central Blood Station(222002),2 Lianyungang First People’s Hospital,Lianyungang(222002),China |
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| Abstract: | Objective To observe the changes of serum SF,VEGF and HGF levels and after transfusion of red blood cells(RBC) in patients with chronic nephritis.Methods Serum SF(with RIA) and serum VEGF,HGF(with ELISA) levels were measured in 30 patients with chronic nephritis both before and after a course of transfusion of RBC and 35 controls.Results Before transfusion the serum SF levels in the patients were significantly lower than those in controls(P<0.01),while the serum VEGF,HGF levels were prominently higher(P<0.01),after a course of 2 weeks transfusion of RBC the serum SF,VEGF and HGF levels in the patients were no significant difference from those in controls(P>0.05).Conclusion Determination of serum SF,VEGF and HGF levels were clinically useful for the progress,prognosis and judgement of chronic nephritis. |
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| Keywords: | chronic nephritis serum ferritin(SF) vascular endothelial growth factor(VEGF) hepatocyte growth factor(HGF) |
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