| 活化T细胞抗原p140在肾移植患者T淋巴细胞的表达 |
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| 引用本文： | 李州利,石炳毅,蔡明,周文强,王亚炜,贾卫,金伯泉. 活化T细胞抗原p140在肾移植患者T淋巴细胞的表达[J]. 解放军医学杂志, 2002, 27(10): 862-864,T001 |
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| 作者姓名： | 李州利 石炳毅 蔡明 周文强 王亚炜 贾卫 金伯泉 |
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| 作者单位： | 1. 100091,北京,解放军第309医院
2. 第四军医大学免疫学教研室 |
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| 基金项目： | 全军医学科研"十五"计划重大项目基金资助课题(编号012097) |
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| 摘 要： | 用免疫荧光染色和流式细胞术观察P140的表达,并用移植肾穿刺活检证实排斥反应。结果表明,P140在肾移植患者淋巴细胞亚群及活化T细胞有弱表达,存在排斥反应时表达增强,提示P140为一种新的移植抗原诱导的T细胞活化分子;P140在肾移植患者排斥反应时表达增强,有可能成为特异的判别指标。
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| 关 键 词： | 活化T细胞 白细胞分化抗原 肾移植 T淋巴细胞 表达 |
EXPRESSION OF AN ACTIVATED T CELL ANTIGEN p140 IN ALLOGRAFT RENAL TRANSPLANTATION |
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| Li Zhouli,Shi Bingyi,Cai Ming et al. Hospital of PLA,Beijing. EXPRESSION OF AN ACTIVATED T CELL ANTIGEN p140 IN ALLOGRAFT RENAL TRANSPLANTATION[J]. Medical Journal of Chinese People's Liberation Army, 2002, 27(10): 862-864,T001 |
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| Authors: | Li Zhouli Shi Bingyi Cai Ming et al. Hospital of PLA Beijing |
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| Affiliation: | Li Zhouli,Shi Bingyi,Cai Ming et al. 309 Hospital of PLA,Beijing 100091 |
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| Abstract: | To investigate expression of the novel membrane molecule p140 on activated T cell in patients after renal transplantation, im-munofluoescence staining and FCM analysis were utilized to monitor the expression of p140, and transplanted renal biopsy was employed to confirm acute allograft rejection. p140 is a transplantion antigen-induced molecule on activated T cells. It expresses weakly on T cells in patients after renal transplantation, but expresses remarkably during actue allograft rejection. |
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| Keywords: | activated T cell leucocyte diffferentiation antigen kidney transplantation |
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