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A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice |
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| Authors: | Ruklanthi de Alwis Esther S. Gan Shiwei Chen Yan Shan Leong Hwee Cheng Tan Summer L. Zhang Clement Yau Jenny G.H. Low Shirin Kalimuddin Daiki Matsuda Elizabeth C. Allen Paula Hartman Kyoung-Joo Jenny Park Maher Alayyoubi Hari Bhaskaran Adrian Dukanovic Yanjie Bao Brenda Clemente Eng Eong Ooi |
| Affiliation: | 1. Viral Research and Experimental Medicine Center, SingHealth Duke-NUS Academic Medical Center, Singapore, Singapore;2. Program in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore;3. Department of Infectious Disease, Singapore General Hospital, Singapore, Singapore;4. Arcturus Therapeutics, Inc., 10628 Science Center Drive, San Diego, CA 92121, USA |
| Abstract: |  |
| Keywords: | SARS-CoV-2 conventional mRNA self-amplifying RNA STARR LUNAR-COV19 COVID-19 vaccine coronavirus |
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