首页 | 本学科首页   官方微博 | 高级检索  
检索        


Progressive immune dysfunction with advancing disease stage in renal cell carcinoma
Authors:David A Braun  Kelly Street  Kelly P Burke  David L Cookmeyer  Thomas Denize  Christina B Pedersen  Satyen H Gohil  Nicholas Schindler  Lucas Pomerance  Laure Hirsch  Ziad Bakouny  Yue Hou  Juliet Forman  Teddy Huang  Shuqiang Li  Ang Cui  Derin B Keskin  John Steinharter  Catherine J Wu
Institution:1. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA;2. Harvard Medical School, Boston, MA 02215, USA;3. Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA;4. Department of Data Science, Dana-Farber Cancer Institute, Boston, MA 02215, USA;5. Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02215, USA;6. Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA 02215, USA;7. Department of Pathology, Brigham and Women''s Hospital, Boston, MA 02115, USA;8. Section for Bioinformatics, Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark;9. Center for Genomic Medicine, Rigshospitalet - Copenhagen University Hospital, Copenhagen, Denmark;10. Department of Academic Hematology, University College London, London, UK;11. Translational Immunogenomics Lab, Dana-Farber Cancer Institute, Boston, MA 02215, USA;12. Harvard-MIT Division of Health Sciences and Technology, MIT, Cambridge, MA 02139, USA;13. Division of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA;14. Division of Urologic Surgery, Brigham and Women''s Hospital, Boston, MA 02115, USA;15. Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, MA 02215, USA;16. Evergrande Center for Immunologic Diseases, Harvard Medical School & Brigham and Women''s Hospital, Boston, MA 02115, USA
Abstract:
><ol class=
  • Download : Download high-res image (188KB)
  • Download : Download full-size image
  • Keywords:single-cell RNA sequencing  CD8 T cell exhaustion  tumor-associated macrophages  cell-cell interaction  cancer immunotherapy  immune cell atlas  clear cell renal cell carcinoma
    本文献已被 ScienceDirect 等数据库收录!
    设为首页 | 免责声明 | 关于勤云 | 加入收藏

    Copyright©北京勤云科技发展有限公司  京ICP备09084417号