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Atrial resting membrane potential confers sodium current sensitivity to propafenone,flecainide and dronedarone
Authors:Andrew P. Holmes  Priyanka Saxena  S. Nashitha Kabir  Christopher O’Shea  Stefan M. Kuhlmann  Suranjana Gupta  Dannie Fobian  Clara Apicella  Molly O’Reilly  Fahima Syeda  Jasmeet S. Reyat  Godfrey L. Smith  Antony J. Workman  Davor Pavlovic  Larissa Fabritz  Paulus Kirchhof
Affiliation:1. Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, United Kingdom;2. Institute of Clinical Sciences, University of Birmingham, Birmingham, United Kingdom;3. Institute of Cardiovascular & Medical Sciences, University of Glasgow, Glasgow, United Kingdom;4. Department of Cardiology, Charité-Universitätsmedizin, Berlin, Germany;5. Computational Neurophysiology Lab, Indian Institute of Technology (IIT) Bombay, Mumbai, India;6. Equipe Gametes to Birth, Institut Cochin, U1016 INSERM, Paris, France;7. Department of Cardiology, University Hospital Birmingham, Birmingham, United Kingdom;11. University Heart and Vascular Center, UKE Hamburg, Hamburg, Germany;12. German Center for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, Hamburg, Germany
Abstract:
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  • Keywords:Atrial action potential  Atrial fibrillation  Dronedarone  Flecainide  PITX2  Propafenone  Resting membrane potential
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