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Atrial resting membrane potential confers sodium current sensitivity to propafenone,flecainide and dronedarone
Authors:Andrew P Holmes  Priyanka Saxena  S Nashitha Kabir  Christopher O’Shea  Stefan M Kuhlmann  Suranjana Gupta  Dannie Fobian  Clara Apicella  Molly O’Reilly  Fahima Syeda  Jasmeet S Reyat  Godfrey L Smith  Antony J Workman  Davor Pavlovic  Larissa Fabritz  Paulus Kirchhof
Institution:1. Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, United Kingdom;2. Institute of Clinical Sciences, University of Birmingham, Birmingham, United Kingdom;3. Institute of Cardiovascular & Medical Sciences, University of Glasgow, Glasgow, United Kingdom;4. Department of Cardiology, Charité-Universitätsmedizin, Berlin, Germany;5. Computational Neurophysiology Lab, Indian Institute of Technology (IIT) Bombay, Mumbai, India;6. Equipe Gametes to Birth, Institut Cochin, U1016 INSERM, Paris, France;7. Department of Cardiology, University Hospital Birmingham, Birmingham, United Kingdom;11. University Heart and Vascular Center, UKE Hamburg, Hamburg, Germany;12. German Center for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, Hamburg, Germany
Abstract:
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  • Keywords:Atrial action potential  Atrial fibrillation  Dronedarone  Flecainide  PITX2  Propafenone  Resting membrane potential
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