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Immunomodulation by targeted anticancer agents
Authors:Giulia Petroni  Aitziber Buqué  Laurence Zitvogel  Guido Kroemer  Lorenzo Galluzzi
Affiliation:1. Department of Radiation Oncology, Weill Cornell Medical College, New York, NY, USA;2. Gustave Roussy Cancer Center, Villejuif, France;3. INSERM U1015, Villejuif, France;4. Center of Clinical Investigations in Biotherapies of Cancer (CICBT) 1428, Villejuif, France;5. Faculty of Medicine, Paris-Saclay University, Le Kremlin-Bicêtre, France;6. Equipe Labellisée Par La Ligue Contre le Cancer, Centre de Recherche des Cordeliers, INSERM U1138, Université de Paris, Sorbonne Université, Paris, France;7. Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France;8. Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France;9. Suzhou Institute for Systems Medicine, Chinese Academy of Medical Sciences, Suzhou, China;10. Department of Women''s and Children''s Health, Karolinska University Hospital, Stockholm, Sweden;11. Sandra and Edward Meyer Cancer Center, New York, NY, USA;12. Caryl and Israel Englander Institute for Precision Medicine, New York, NY, USA;13. Department of Dermatology, Yale School of Medicine, New Haven, CT, USA;14. Université de Paris, Paris, France
Abstract:
Keywords:BRAF  CDK4/CDK6  CGAS signaling  DNA damage response  EGFR  immune checkpoint blockers  immunogenic cell death  KRAS  TGF-β
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