糖化血红蛋白与糖尿病合并慢性心力衰竭严重程度的相关性

目的研究糖化血红蛋白(HbA1c)与糖尿病患者合并慢性心力衰竭严重程度之间的相关性。方法 86例糖尿病合并慢性心力衰竭患者均检测其血HbA1c及N末端B型利钠肽前体(NT-proBNP)水平,依据HbA1c水平分为3组:A组29例(HbA1c<6.5%)、B组29例(6.5%≤HbA1c<8.0%)、C组28例(HbA1c≥8.0%),对所观察指标进行统计学分析。结果和A组相比,B、C两组NT-proBNP水平均明显升高(P<0.05),且C组NT-proBNP水平较B组更高(P<0.01),三组患者的NT-proBNP与HbA1c水平间呈正相关(P<0.01)。结论糖尿病合并慢性心力衰竭患者的HbA1c水平与NT-proBNP呈正相关,临床上可根据HbA1c水平对糖尿病合并慢性心力衰竭患者进行危险分层。

The study of the relativity between glycosylated hemoglob and chronic heart failure in diabetic patients

Objective To study the the relationship between glycosylated hemoglob（HbA1c） and chronic heart failure in diabetic patients.Methods 86 cases of diabetic with chronic heart failure patients were divided into 3 groups according to the HbA1c levels： 29 cases in A group（HbA1c 6.5%）,29 cases in group B（6.5% ≤ HbA1c 8.0%）,28 cases in group C（HbA1c ≥ 8%）,All patients were detected the HbA1c and NT-proBNP levels,and deal with the data by statistical analysis.Results Compared with the A group,the NT-proBNP level of B and C group increased significantly（P 0.05）,and C group higher was than in group B（P 0.01）.The HbA1c and NT-proBNP levels of three groups are positively correlated（P 0.01）.Conclusion The HbA1c and NT-proBNP levels are positively correlated in diabetic patients with chronic heart failure.we can conduct the risk stratification of them according to the levels of HbA1c.