代谢综合征患者脉压与心脑血管疾病的相关性

目的：探讨脉压（PP）、脉压指数（PPI）与代谢综合征（MS）患者心脑血管疾病的相关性。方法：选择近5年我院门诊和住院MS患者204例（男138例．女66例），按PPI≤0．40、0．41～0．50、0．51～0．60、〉0．60分为4组，按PP≤40mmHg、41～60mmHg、61～80mmHg、〉80mmHg（1mmHg=0．133kPa）分为4组．分析各组间PP、PPI与心脑血管疾病发生率的相关性。结果：①不同组的PP、PPI在吸烟、饮酒、体重指数（BMI）、血糖、腹围、舒张压（DBP）、甘油三脂（TG）、高密度脂蛋白-胆固醇（HDL-C）、及低密度脂蛋白-胆固醇（LDL—C）方面无显著差别（P〉0．05），在年龄、收缩压（SBP）方面差异有显著性（P〈0．05～〈0．01）；不同组的PP及PPI的左室肥厚、冠心病、心功能不全、脑卒中发生率有显著性差异（P均〈0．05）；左室肥厚、冠心病、心功能不全、脑卒中的发生率与患者年龄、收缩压、脉压、脉压指数有显著相关性EXP（B）=1．614～3．340，P均〈0．05]。结论：MS患者心脑血管疾病与年龄、SBP、PP、PPI等因素有关，与PPI的关系更为密切。

Correlation among pulse pressure and cardiovascular and cerebrovascular diseases in patients with metabolic syndrome

Objective： To investigate the correlation between pulse pressure, and cardiovascular and cerebrovascular diseases in patients with metabolic syndrome （MS）. Methods： A total of 204 outpatients or inpatients with MS of our hospital in the past five years （138 male cases and 66 female cases） were chose. They were divided into four groups by PPI ≤0. 40, 0.41-0.50, 0. 51-0. 60, 〉0. 60; and into four groups by PP ≤ 40 mmHg, 41-60 mmHg, 61-80 mmHg, 〉 80mmHg （1mmHg：0. 133kPa）, and the correlation among PP, PPI and incidence of cardiovascular and cerebrovascular diseases was analyzed. Results： There was no significant difference in smokers, drinkers, BMI, blood sugar, abdominal circumference, diastolic blood pressure （DBP）, triglyceride （TG）, high-density lipnprotein （HDL-C） and low-density lipoprotein （LDL-C） among the different groups divided by PP and PPI （P〉0.05）, there were significant differences in age and systolic blood pressure （SBP） （P〈0.05-〈0.01）. There were significant differences in left ventricular hypertrophy, and incidence of coronary heart disease, heart failure and stroke among the different groups divided by PP and PPI （P〈0. 05 all）. Left ventricular hypertrophy, coronary heart disease, heart failure and stroke were significantly correlated to the age, systolie blood pressure, pulse pressure and pulse pressure index EXP （B） =1. 614-3. 340, P〈0. 05]. Conclusion： The incidence of cardiovascular and cerebrovascular diseases in MS patients are related to their age, SBP, PP, PPI, and correlation to PPI is more closely.