| 帕罗西汀治疗脑卒中后抑郁障碍的对照研究 |
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| 引用本文： | 袁文林. 帕罗西汀治疗脑卒中后抑郁障碍的对照研究[J]. 中国实用神经疾病杂志, 2004, 7(3): 8-9 |
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| 作者姓名： | 袁文林 |
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| 作者单位： | 江苏盐城市第四人民医院神经内科,盐城,224003 |
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| 摘 要： | 目的比较帕罗西汀和阿米替林对脑卒中后抑郁障碍的疗效及神经功能康复的影响。方法 应用帕罗西汀和阿米替林进行对照治疗研究,采用汉密尔顿抑郁量表(HAMD)和爱丁堡-斯堪的纳维亚卒中量表(MESSS)评定疗效。结果 帕罗西汀和阿米替林对脑卒中后抑郁障碍的疗效相当,但帕罗西汀起效较快,且不良反应较少而轻微。结论 帕罗西汀可明显改善脑卒中后抑郁障碍的程度,并能促进神经功能康复。
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| 关 键 词： | 帕罗西汀 阿米替林 抑郁障碍 脑卒中 |
| 修稿时间： | 2004-02-13 |
A comparative study of paroxetine in the treatment of post - stroke depression |
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| Yuan Werdin. A comparative study of paroxetine in the treatment of post - stroke depression[J]. Chinese Journal of Practical Neruous Diseases, 2004, 7(3): 8-9 |
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| Authors: | Yuan Werdin |
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| Affiliation: | Yuan Werdin. Department of Neurology,the fourth people's hospital of Yancheng,Yancheng 224003 |
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| Abstract: | Objective To compare the effectiveness on depressive symptoms and nervous function of the stroke patients between paroxetine and amitriptyline.Methods All patients were randomly assigned with paroxetine or amitriptyline for 6 weeks.The therapeutic effects were assessed with HAMD and MESSS scales. Results The findings indicated that the efficacy of paroxetine was similar to that of amitriptyline, however paroxetine took effect more quickly and its side effects were less than that of amitriptyline. Conclusion Paroxetine can significantly improve the the depressive symptoms and neurological functions. |
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| Keywords: | Paroxetine Amitriptyline Depressive symptoms Stroke |
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