Screening of human populations for mutations induced by environmental pollutants: Use of human lymphocyte system |
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Authors: | A. T. Natarajan G. Obe |
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Affiliation: | 1. Department of Radiation Genetics and Chemical Mutagenesis, Sylvius Laboratories, Wassenaarseweg 72, University of Leiden The Netherlands;2. J. A. Cohen Institute of Radiation Pathology and Radiation Protection, Leiden, The Netherlands;3. Institut für Genetik, Freie Universität Berlin, Arnimallee 5-7, D-1000 Berlin 33, Federal Republic of Germany |
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Abstract: | Mutagenic effects of physical (different irradiations), chemical (alcohol, tobacco smoke, drugs, chemicals at the working place, etc.), and biological (viruses) agents in man can be evaluated by screening for chromosomal aberrations in the peripheral blood lymphocytes. This human lymphocyte test system is described and the results obtained are discussed. |
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