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幽门螺杆菌与胃粘膜相关淋巴组织淋巴瘤关系探讨
引用本文:李娅琳,周雁,张晓晖. 幽门螺杆菌与胃粘膜相关淋巴组织淋巴瘤关系探讨[J]. 临床消化病杂志, 2002, 14(3): 101-102
作者姓名:李娅琳  周雁  张晓晖
作者单位:1. 云南省人民医院消化科,昆明,650032
2. 第四军医大学附属西京医院病理科
摘    要:目的:通过检测胃粘膜相关淋巴组织(MALT)淋巴瘤中的幽门螺杆菌(HP),探讨HP与胃粘膜相关淋巴组织淋巴瘤的关系。方法:收集26例胃MALT淋巴瘤,20例淋巴性胃炎与30例轻度浅表性胃炎的胃粘膜组织病理石蜡切片行0.25%甲苯胺蓝染色,显微镜检查HP,结果:胃MALT淋巴瘤组,淋巴细胞性胃炎组及轻度浅表性胃炎组的HP感染率分别为88.48%,65.00%,43.33%,经统计学分析,差异有显著性(P<0.05),结论:HP感染与胃MALT淋巴瘤的发生有密切的关系,建议在对胃MALT淋巴瘤行化疗的同时行根除HP治疗。

关 键 词:胃粘膜相关淋巴组织淋巴瘤 幽门螺杆菌 相关关系
文章编号:1005-541X(2002)03-101-02
修稿时间:2001-12-04

Study of Relationship Between Helicobacter Pylori and Gastric Mucosa Associated Lymphoid Tissue Lymphoma
Li Ya lin,Zhang Xiao hui,Zhou Yan. Study of Relationship Between Helicobacter Pylori and Gastric Mucosa Associated Lymphoid Tissue Lymphoma[J]. Chinese Journal of Clinical Gastroenterology, 2002, 14(3): 101-102
Authors:Li Ya lin  Zhang Xiao hui  Zhou Yan
Affiliation:Li Ya lin,Zhang Xiao hui,Zhou Yan Department of Gastroenterology,Yunnan Province First People's Hospital,Kunming 650032
Abstract:Purpose: To investigate the relationship between helicobacter pylori(HP) and gastric mucosa associated lymphoid tissues(MALT) lymphoma, by detection of HP in MALT lymphoma. Methods: 26 cases of gastric MALT lymphoma, 20 cases of lymphocytic gastritis and 30 cases of mild superficial gastritis were studied. 0.25% luidine blue staining was used to detect the HP. Results: The HP positive rate of gastric MALT lymphoma, lymphocytic gastritis and mild superficial gastritis were 88.48%, 65.00%, 43.33 %, respectively. The HP positive rate of gastric MALT lymphoma was siginificantly higher than that of lymphocytic gastritis and mild superficial gastritis(P<0.05). Conclusion: Gastric MALT lymphoma correlates colsely to HP infection. Antibiotic should be used in the therapy besides the chemotherapy.
Keywords:Mucosa associated lymphoid tissue Lymphoma Helicobacter pylori
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