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^18F-FDG SPECT/CT同机融合显像在原发灶不明转移癌中的临床应用
引用本文:林小敏,蔡志华,唐明灯,倪雷春,林端瑜.^18F-FDG SPECT/CT同机融合显像在原发灶不明转移癌中的临床应用[J].福建医药杂志,2009,31(3):106-108.
作者姓名:林小敏  蔡志华  唐明灯  倪雷春  林端瑜
作者单位:福建省肿瘤医院核医学科,350014
摘    要:目的探讨^18F-FDG SPECT/CT同机融合显像在原发灶不明转移癌中的应用价值。方法对51例行^18F-FDG SPECT/CT同机融合显像,同时获得SPECT、CT及两者的融合图像,至少由2名核医学科主治以上医师对图像进行双盲阅片诊断,结果与病理或随访结论相比较。结果^18F-FDG SPECT/CT融合显像、单独SPECT显像及单独CT显像对原发灶的检出率分别为43.13%(22/51)、31.37%(16/51)、21.57%(11/51),差别有统计学意义(P〈0.05)。^18F-FDG SPECT/CT同机融合显像灵敏度为88.00%,特异性为84.62%,准确度为86.27%,阳性预测值为84.62%,阴性预测值为88.00%。经SPECT/CT同机融合显像检查后32例原发灶不明转移癌的临床治疗方案得以确定或调整,其中10例临床分期得以提高。结论^18F-FDG SPECT/CT同机融合显像对原发不明转移癌的诊断、再分期和治疗有重要临床价值。

关 键 词:SPECT/CT融合显像  原发灶  转移癌  脱氧葡萄糖

Clinical application of the ~(18)F-FDG SPECT/CT fusion imaging in detecting carcinoma of unknown primary site
Lin Xiaomin,Cai Zhihua,Tang Mingdeng,Ni Leichun,Lin Duanyu.Clinical application of the ~(18)F-FDG SPECT/CT fusion imaging in detecting carcinoma of unknown primary site[J].Fujian Medical Journal,2009,31(3):106-108.
Authors:Lin Xiaomin  Cai Zhihua  Tang Mingdeng  Ni Leichun  Lin Duanyu
Institution:Lin Xiaomin,Cai Zhihua,Tang Mingdeng,Ni Leichun,Lin Duanyu.Department of Nuclear Medicine,Fujian Provincial Tumor Hospital,Fuzhou 350014,China
Abstract:Objective To investigate the role of 18F-FDG SPECT/CT fusion imaging in detecting carcinoma of unknown primary site(CUP).Methods Fifty-one with CUP syndrome were examined by the 18F-FDG SPECT/CT fusion imaging.The images of SPECT alone,CT alone and SPECT/CT were blindly interpreted by more than two experienced nuclear medicine specialist.The results of images were compared to the conclusion of pathology or follow-up.Results The detection rate of SPECT/CT fusion imaging(43.13%,22/51)was higher than that of S...
Keywords:SPECT/CT fusion imaging  Primary lesion  Metastases  Deoxyglucose  
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